Evidence map›Paper›PMID 31603514›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2021

Fertility History and Cognitive Function in Late Life: The Case of Mexico.

Joseph L Saenz, Carlos Díaz-Venegas, Eileen M Crimmins

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Observational
  2. Article
  3. Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  4. Article
  5. Article
  6. Childbearing Histories and Midlife Cognition: Accounting for Early Life Factors.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Fertility History and Risk of Cognitive Impairment Among Older Parents in the United States.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  16. Article
  17. Review
  18. Review
  19. Gender-Based Pathways to Cognitive Aging in the Mexican-Origin Population in the United States: The Significance of Work and Family.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph L SaenzUniversity of Southern California, Davis School of Gerontology, Los Angeles.
Carlos Díaz-VenegasMax Planck Institute for Demographic Research, Rostock, Germany.
Eileen M CrimminsUniversity of Southern California, Davis School of Gerontology, Los Angeles.

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, HIRAM BELTRAN-SANCHEZ · 1999 to 2026
$17.9M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
USC Resource Center for Minority Aging Research (US-RCMAR)P30AG043073 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EMMA AGUILA, JENNIFER A AILSHIRE · 2012 to 2026
$10.1M
Education and the Life-Course Pathways of Cognitive Impairment, Dementia, and Cognitive Decline in the United States and MexicoR00AG058799 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SAENZ, JOSEPH · 2020 to 2022
$745k
Education and the Life-Course Pathways of Cognitive Impairment, Dementia, and Cognitive Decline in the United States and MexicoK99AG058799 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SAENZ, JOSEPH · 2018 to 2019
$153k
NIA NIH HHS K99 AG058799NIA NIH HHS P30 AG017265NIA NIH HHS P30 AG043073NIA NIH HHS R00 AG058799NIA NIH HHS R01 AG018016NIA NIH HHS T32 AG000037
6 · The paper itself

Abstract

objectivesMexico is aging rapidly, which makes identification of life-course factors influencing cognition a public health priority. We evaluate how the number of children one has relates to cognition in Mexico, a rapidly aging country that experienced fertility declines across recent cohorts of older people.

methodWe analyze older adults (age 50+, n = 11,380) from the 2015 Mexican Health and Aging Study. Respondents were categorized by number of children ever born (0-1, 2-3, 4-5, 6+). Using ordinary least squares regression, we estimate independent associations between fertility history and cognition accounting for demographic, socioeconomic, health, and psychosocial factors.

resultsWe observed an inverse U-shaped relationship between number of children (peaking at 2-3 children) and cognitive function, regardless of gender. In regression analyses adjusted for confounding variables, having 0-1 (vs 2-3 children) was associated with poorer cognitive function only for females. Regardless of gender, having 6+ (vs 2-3 children) was associated with poorer cognitive function. These associations remained significant even after accounting for socioeconomic, health, employment, and psychosocial factors. DISCUSSION: Our results suggest fertility history may play a role in late-life cognitive health and provide evidence that both low and high fertility may relate to poorer cognitive function. We discuss differences by gender.

Indexed as

CognitionFertilityParityPsychologySocioeconomic FactorsCognitive AgingCorrelation of DataDemographyFemaleHealth StatusHumansMaleMexicoMiddle AgedPregnancyPublic HealthChildrenCognitionLatin America

Identifiers

PMID31603514
PMCPMC7955970

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.