Evidence map›Paper›PMID 31602618›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Data Management in Computational Systems Biology: Exploring Standards, Tools, Databases, and Packaging Best Practices.

Natalie J Stanford, Martin Scharm, Paul D Dobson, Martin Golebiewski, Michael Hucka, Varun B Kothamachu, David Nickerson, Stuart Owen, Jürgen Pahle, Ulrike Wittig and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Making PBPK models more reproducible in practice.Briefings in bioinformatics · 2024
    Article
  2. Microbiome modeling: a beginner's guide.Frontiers in microbiology · 2024
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Natalie J StanfordSchool of Computer Science, University of Manchester, Manchester, UK.
Martin ScharmDepartment of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany.
Paul D DobsonSchool of Computer Science, University of Manchester, Manchester, UK.
Martin GolebiewskiHeidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.
Michael HuckaComputing and Mathematical Sciences, California Institute of Technology, Pasadena, CA, USA.
Varun B KothamachuSignalling ISP, The Babraham Institute, Cambridge, UK.
David NickersonAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Stuart OwenSchool of Computer Science, University of Manchester, Manchester, UK.
Jürgen PahleBIOMS/BioQuant, Heidelberg University, Heidelberg, Germany. juergen.pahle@bioquant.uni-heidelberg.de.
Ulrike WittigHeidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.
Dagmar WaltemathMedical Informatics, University Medicine Greifswald, Greifswald, Germany.
Carole GobleSchool of Computer Science, University of Manchester, Manchester, UK.
Pedro MendesCentre for Quantitative Medicine, University of Connecticut, Farmington, CT, USA.
Jacky SnoepSchool of Computer Science, University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computational systems biology involves integrating heterogeneous datasets in order to generate models. These models can assist with understanding and prediction of biological phenomena. Generating datasets and integrating them into models involves a wide range of scientific expertise. As a result these datasets are often collected by one set of researchers, and exchanged with others researchers for constructing the models. For this process to run smoothly the data and models must be FAIR-findable, accessible, interoperable, and reusable. In order for data and models to be FAIR they must be structured in consistent and predictable ways, and described sufficiently for other researchers to understand them. Furthermore, these data and models must be shared with other researchers, with appropriately controlled sharing permissions, before and after publication. In this chapter we explore the different data and model standards that assist with structuring, describing, and sharing. We also highlight the popular standards and sharing databases within computational systems biology.

Indexed as

Computational BiologyDatabases, FactualData ManagementSystems BiologyDatabasesData storageFAIRMetadataModel storageReproducible researchStandards

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.