Evidence map›Paper›PMID 31602614›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Probing the RNA-Binding Proteome from Yeast to Man: Major Advances and Challenges.

Benedikt M Beckmann, Sander Granneman

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Post-transcriptional control of fungal cell wall synthesis.Cell surface (Amsterdam, Netherlands) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Benedikt M BeckmannMolecular Infection Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Berlin, Germany. benedikt.beckmann@iri-lifesciences.de.
Sander GrannemanCentre for Systems and Synthetic Biology (SynthSys), University of Edinburgh, Edinburgh, UK.
Humboldt-Universität zu Berlin · DEUniversity of Edinburgh · GB

Funding

Medical Research Council MR/R008205/1
6 · The paper itself

Abstract

RNA-binding proteins are important for core cellular processes such as mRNA transcription, splicing, transport, translation, and degradation. Recently, hundreds of novel RNA-binders have been identified in vivo in various organisms and cell types. We discuss the RNA interactome capture technique which enabled this boost in identifying new RNA-binding proteins in eukaryotes. A focus of this chapter, however, is the presentation of different challenges and problems that need to be addressed to be able to understand the conserved mRNA-bound proteomes from yeast to man.

Indexed as

AnimalsMiceModels, BiologicalProteomeRNA-Binding ProteinsRNA, MessengerSaccharomyces cerevisiaeProteomeRNA-Binding ProteinsRNA, MessengerEukaryotesmRNA processingProteomeRNA-binding proteins

Identifiers

PMID31602614
OpenAlexW2979610781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.