Evidence map›Paper›PMID 31602584›Full record

ArticleArchives of sexual behavior2020

PrEP Awareness, Uptake, Barriers, and Correlates Among Adolescents Assigned Male at Birth Who Have Sex with Males in the U.S.

Kathryn Macapagal, Ashley Kraus, Aaron K Korpak, Kyle Jozsa, David A Moskowitz

Open access · greenAbstract read
In one paragraph

Article in Archives of sexual behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Psychosocial correlates of condom use among Black adolescents in the United States: A meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  10. Parent-Adolescent Relationship Quality, Sexual Health Communication, and Willingness to Support Pre-Exposure Prophylaxis for HIV: A Qualitative Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026
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  16. HIV Prevention Behaviors among LGBTQ+ Adolescents: the Protective Role of LGBTQ+-Inclusive School Resources.Prevention science : the official journal of the Society for Prevention Research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kathryn MacapagalDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue, Suite 1400, Chicago, IL, 60611, USA. kathryn.macapagal@northwestern.edu.ORCID 0000-0002-1208-6097
Ashley KrausDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue, Suite 1400, Chicago, IL, 60611, USA.
Aaron K KorpakDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue, Suite 1400, Chicago, IL, 60611, USA.
Kyle JozsaDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue, Suite 1400, Chicago, IL, 60611, USA.
David A MoskowitzDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue, Suite 1400, Chicago, IL, 60611, USA.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)TL1TR001423 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCCOLLEY, SUSANNA A · 2015 to 2023
$5.0M
NCATS NIH HHS TL1 TR001423
6 · The paper itself

Abstract

In May 2018, the US Food and Drug Administration approved daily oral pre-exposure prophylaxis (PrEP) for adolescents under age 18. Although this is an important step toward HIV prevention for adolescents assigned male at birth who have sex with males (AMSM), limited research exists to gauge their awareness of PrEP as a prevention option. Additionally, the attitudes and perceived barriers regarding PrEP among this population have not been well studied. We conducted an online survey from February to April 2018, in which 219 AMSM age 15-17 read a description of PrEP, and then answered questions about PrEP awareness, perceived barriers, and demographic and behavioral correlates. A slight majority (54.8%) had heard of PrEP before, and 56.1% did not know how they would access PrEP. Of those who had heard of PrEP, 2.5% had ever used it. Most had first learned about PrEP online, through media or geosocial networking (GSN) applications to meet male partners. Those who had heard of PrEP were more likely to be older, to have used GSN applications, and to have greater HIV knowledge. Not knowing how to access PrEP was predicted by having had more partners, lower HIV knowledge, and never having talked to a provider about PrEP. Believing that one could not afford PrEP was predicted by greater perceived risk of HIV. Findings suggest moderate awareness of PrEP among AMSM, that youth at greater risk of HIV may perceive greater barriers, and that online spaces can play a significant role in increasing PrEP knowledge and reducing implementation barriers.

Indexed as

AdolescentAdultFemaleHIV InfectionsHomosexuality, MaleHumansMalePre-Exposure ProphylaxisSexual PartnersSurveys and QuestionnairesAdolescent sexual behaviorHIV/AIDSMen who have sex with menPre-exposure prophylaxisSexual and gender minoritiesSexual orientation

Identifiers

PMID31602584
PMCPMC7263631
OpenAlexW2979620534

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.