Evidence map›Paper›PMID 31602571›Full record

ArticleInternational journal of hematology2019

Successful granulocyte apheresis using medium molecular weight hydroxyethyl starch.

Mai Nanya, Kimiko Yurugi, Itaru Kato, Hidefumi Hiramatsu, Hiroshi Kawabata, Tadakazu Kondo, Tomoki Iemura, Rie Hishida, Erika Shibutani, Keiko Matsui and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Mai NanyaDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Kimiko YurugiDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Itaru KatoDepartment of Pediatrics, Kyoto University, Kyoto, Japan.
Hidefumi HiramatsuDepartment of Pediatrics, Kyoto University, Kyoto, Japan.
Hiroshi KawabataDepartment of Hematology and Oncology, Kyoto University, Kyoto, Japan.
Tadakazu KondoDepartment of Hematology and Oncology, Kyoto University, Kyoto, Japan.
Tomoki IemuraDepartment of Hematology and Oncology, Kyoto University, Kyoto, Japan.
Rie HishidaDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Erika ShibutaniDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Keiko MatsuiDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yoko NakagawaDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Norimi NiwaDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yasunari KasaiDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Joseph M RoigMedical Affairs, Terumo BCT, Lakewood, CO, USA.
Yasuyuki AraiDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yasuo MiuraDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Akifumi Takaori-KondoDepartment of Hematology and Oncology, Kyoto University, Kyoto, Japan.
Taira MaekawaDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Hideyo HiraiDepartment of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. hhirai@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0002-9036-4865
Kyoto University Hospital · JPKyoto University · JPKanazawa Medical University · JPTerumo (United States) · US

Funding

Japan Agency for Medical Research and Development ACT-MSJapan Agency for Medical Research and Development JP17bm0504008Japan Society for the Promotion of Science 16K07171Japan Society for the Promotion of Science 18K08354
6 · The paper itself

Abstract

Granulocyte transfusion (GTX) is a therapeutic option for severe bacterial or fungal infection in patients with sustained neutropenia after chemotherapy or stem cell transplantation. However, high molecular weight hydroxyethyl starch (HES), which has been used for selective sedimentation of red blood cells during apheresis, is not easily available in many countries including Japan. In this study, we evaluated the efficiency of granulocyte collection using medium molecular weight HES (130 kDa) in combination with the Spectra Optia apheresis system. Apheresis was performed for 2 consecutive days from seven donors and the mean total neutrophil yield from the first and second apheresis was 5.27 ± 3.10 × 10

Indexed as

AdultCell CountCytapheresisFemaleGranulocytesHumansHydroxyethyl Starch DerivativesJapanLeukapheresisMaleMiddle AgedMolecular WeightNeutrophilsHydroxyethyl Starch DerivativesApheresisGranulocyte transfusionHydroxyethyl starch (HES)

Identifiers

PMID31602571
OpenAlexW2979392664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.