Evidence map›Paper›PMID 31602529›Full record

ReviewAnnals of intensive care2019

Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d'Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies.

Philippe Le Conte, Nicolas Terzi, Guillaume Mortamet, Fekri Abroug, Guillaume Carteaux, Céline Charasse, Anthony Chauvin, Xavier Combes, Stéphane Dauger, Alexandre Demoule and 26 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Annals of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05916586 (Effect of Short-Term Prednisone Therapy on C-reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05916586 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Short-Term Prednisone Therapy on C-reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers

TypeinterventionalSponsorHeart InitiativeRan2023 to 2024Enrolled101ConditionsAcute Heart FailureArmsPrednisone
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Management of asthma exacerbations in the paediatric population: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2021
    Pooled it
  2. Article
  3. Review
  4. Observational
  5. Review
  6. Article
  7. Antibiotic resistance in chronic respiratory diseases: from susceptibility testing to the resistome.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  8. Article
  9. [Paediatric Life Support].Notfall & rettungsmedizin · 2021
    Review
  10. Review
  11. Observational
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 5 countries.

Philippe Le ConteService d'Accueil des Urgences, CHU de Nantes, 5 allée de l'île gloriette, 44093, Nantes Cedex 1, France.
Nicolas TerziService de Médecine Intensive Réanimation, CHU de Grenoble Alpes, 38000, Grenoble, France. nterzi@chu-grenoble.fr.
Guillaume MortametService de Réanimation Pédiatrique, CHU de Grenoble Alpes, 38000, Grenoble, France.
Fekri AbrougService de réanimation, CHU de Monastir, Monastir, Tunisia.
Guillaume CarteauxService de MIR, Hôpital Henri Mondor, APHP, Créteil, France.
Céline CharassePediatric Emergency Department, CHU Pellegrin Enfants, Bordeaux, France.
Anthony ChauvinService des Urgences, Hôpital Lariboisière, APHP, Paris, France.
Xavier CombesService des Urgences, CHU de la Réunion, Saint-Denis, France.
Stéphane DaugerPediatric Intensive Care Unit, Robert Debré Hospital, APHP, Paris, France.
Alexandre DemouleGroupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie, Médecine Intensive et Réanimation (Département R3S), AP-HP, INSERM, UMRS1158 neurophysiologie respiratoire expérimentale et clinique, Sorbonne Université, Paris, France.
Thibaut DesmettreService des Urgences, CHU de Besançon, Besançon, France.
Stephan EhrmannMédecine Intensive Réanimation, INSERM CIC 1415, réseau CRICS-TriggerSEP, CHRU de Tours and Centre d'Etude des Pathologies Respiratoires, INSERM U1100, faculté de médecine, Université de Tours, Tours, France.
Bénédicte Gaillard-Le RouxPediatric Intensive Care Unit, Women and Children's University Hospital, Nantes, France.
Valérie HamelService des Urgences, CHU de Toulouse, Toulouse, France.
Boris JungService de MIR, CHU de Montpelliers, Montpellier, France.
Sabrina KepkaService des Urgences, CHU de Strasbourg, Strasbourg, France.
Erwan L'HerService de MIR, CHRU de Brest, Brest, France.
Mikaël MartinezPôle Urgences, centre hospitalier du Forez, 42605, Montbrison, France.
Christophe MilésiDépartement de Pédiatrie Néonatale et Réanimations, CHU de Montpellier, Montpellier, France.
Élise MorawiecService de Pneumologie et Réanimation, GH Pitié-Salpêtrière, APHP, Paris, France.
Mathieu OberlinService des Urgences, centre hospitalier de Cahors, Cahors, France.
Patrick PlaisanceService des Urgences, AP-HP, hôpital la Riboisière, Paris, France.
Robin PouyauPediatric Intensive Care Unit, Women-Mothers and Children's University Hospital, Lyon, France.
Chantal Raherisonservice de Pneumologie, CHU de Bordeaux, Pessac, France.
Patrick RayService des Urgences, CHU de Dijon, faculté de médecine de Dijon, Dijon, France.
Mathieu SchmidtINSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Pitié-Salpêtrière Hospital, Medical Intensive Care Unit, Sorbonne Universités, 75651, Paris Cedex 13, France.
Arnaud W ThilleCHU de Poitiers, Médecine Intensive Réanimation, Poitiers, France.
Jennifer TruchotService des Urgences, Hôpital Lariboisière, APHP, Paris, France.
Guillaume ValdenaireService des Urgences, CHU de Bordeaux, Pessac, France.
Julien VauxSAMU 94, CHU Henri Mondor, AP-HP, Créteil, France.
Damien ViglinoINSERM, U1042, University of Grenoble-Alpes, HP2, 38000, Grenoble, France.
Guillaume VoiriotService de réanimation polyvalente, Hôpital Tenon, APHP, Paris, France.
Bénédicte VrignaudPediatric Emergency Department, Women and Children', s University Hospital, Nantes, France.
Sandrine JeanService de Réanimation Pédiatrique, APHP Hôpital Trousseau, 75012, Paris, France.
Eric MariotteService de Médecine Intensive Réanimation, APHP Hôpital Saint Louis, 75010, Paris, France.
Pierre-Géraud ClaretService d'Accueil des Urgences, CHU de Nîmes, 30029, Nîmes, France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Universitaire de Nantes · FRSorbonne Université · FRCentre Hospitalier Universitaire Henri-Mondor · FRUniversité de Bordeaux · FRCentre Hospitalier Régional Universitaire de Brest · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Bordeaux · FRCentre Hospitalier Universitaire de Grenoble · FRCentre Hospitalier Universitaire de Montpellier · FRCentre Hospitalier Universitaire de Nîmes · FRCentre Hospitalier Universitaire de Poitiers · FRCentre Hospitalier Universitaire de Toulouse · FRCHU Dijon Bourgogne · FRDélégation Paris 5 · FRÉcologie Marine Tropicale des Océans Pacifique et Indien · REGroupe Cahors (France) · FRHôpital Femme Mère Enfant · FRHôpitaux Universitaires de Strasbourg · FR

Funding

CSRD VA 1
6 · The paper itself

Abstract

backgroundThe French Emergency Medicine Society, the French Intensive Care Society and the Pediatric Intensive Care and Emergency Medicine French-Speaking Group edited guidelines on severe asthma exacerbation (SAE) in adult and pediatric patients.

resultsThe guidelines were related to 5 areas: diagnosis, pharmacological treatment, oxygen therapy and ventilation, patients triage, specific considerations regarding pregnant women. The literature analysis and formulation of the guidelines were conducted according to the Grade of Recommendation Assessment, Development and Evaluation methodology. An extensive literature research was conducted based on publications indexed in PubMed™ and Cochrane™ databases. Of the 21 formalized guidelines, 4 had a high level of evidence (GRADE 1+/-) and 7 a low level of evidence (GRADE 2+/-). The GRADE method was inapplicable to 10 guidelines, which resulted in expert opinions. A strong agreement was reached for all guidelines.

conclusionThe conjunct work of 36 experts from 3 scientific societies resulted in 21 formalized recommendations to help improving the emergency and intensive care management of adult and pediatric patients with SAE.

Indexed as

AsthmaEmergencyGuidelinesIntensive CarePediatricSevere exacerbation

Identifiers

PMID31602529
PMCPMC6787133
OpenAlexW2980269735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.