Evidence map›Paper›PMID 31602464›Full record

ArticleNucleic acids research2020

PathBank: a comprehensive pathway database for model organisms.

David S Wishart, Carin Li, Ana Marcu, Hasan Badran, Allison Pon, Zachary Budinski, Jonas Patron, Debra Lipton, Xuan Cao, Eponine Oler and 7 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Knowledge-Driven Approaches to Create the MTox700+ Metabolite Panel for Predicting Toxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Pooled it
  2. Metabolomics in Exercise and Sports: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. CladeOScope-GSA: Revealing Evolutionary Associations Across Gene Sets.International journal of molecular sciences · 2026
    Article
  9. Metabolomics Data Analysis with the HMDB.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Identifying Alzheimer's disease-related pathways based on whole-genome sequencing data.Computational and structural biotechnology journal · 2025
    Article
  19. Article
  20. BioPAX in 2024: Where we are and where we are heading.Computational and structural biotechnology journal · 2024
    Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

David S WishartDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Carin LiDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Ana MarcuDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Hasan BadranDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Allison PonDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Zachary BudinskiDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Jonas PatronDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Debra LiptonDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Xuan CaoDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Eponine OlerDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Krissa LiDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Maïlys PaccoudDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Chelsea HongDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
An C GuoDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Christopher ChanDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
William WeiDepartment of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Miguel Ramirez-GaonaDepartment of Plant Breeding, Wageningen University and Research, 6708 PB Wageningen, Gelderland, Netherlands.

Funding

CIHR
6 · The paper itself

Abstract

PathBank (www.pathbank.org) is a new, comprehensive, visually rich pathway database containing more than 110 000 machine-readable pathways found in 10 model organisms (Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus, Drosophila melanogaster, Caenorhabditis elegans, Arabidopsis thaliana, Saccharomyces cerevisiae, Escherichia coli and Pseudomonas aeruginosa). PathBank aims to provide a pathway for every protein and a map for every metabolite. This resource is designed specifically to support pathway elucidation and pathway discovery in transcriptomics, proteomics, metabolomics and systems biology. It provides detailed, fully searchable, hyperlinked diagrams of metabolic, metabolite signaling, protein signaling, disease, drug and physiological pathways. All PathBank pathways include information on the relevant organs, organelles, subcellular compartments, cofactors, molecular locations, chemical structures and protein quaternary structures. Each small molecule is hyperlinked to the rich data contained in public chemical databases such as HMDB or DrugBank and each protein or enzyme complex is hyperlinked to UniProt. All PathBank pathways are accompanied with references and detailed descriptions which provide an overview of the pathway, condition or processes depicted in each diagram. Every PathBank pathway is downloadable in several machine-readable and image formats including BioPAX, SBML, PWML, SBGN, RXN, PNG and SVG. PathBank also supports community annotations and submissions through the web-based PathWhiz pathway illustrator. The vast majority of PathBank's pathways (>95%) are not found in any other public pathway database.

Indexed as

Databases, FactualMetabolic Networks and PathwaysSoftwareAnimalsArabidopsisCaenorhabditis elegansCattleDrosophilaGenomicsHumansMetabolomicsMiceRatsSaccharomyces cerevisiae

Identifiers

PMID31602464
PMCPMC6943071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.