ArticleEuropean thyroid journal2019
Primary versus Tertiary Care Follow-Up of Low-Risk Differentiated Thyroid Cancer: Real-World Comparison of Outcomes and Costs for Patients and Health Care Systems.
Article in European thyroid journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Follow-up and transition of care for low recurrence risk thyroid cancer patients in Canada.European thyroid journal · 2025Guideline
- Economic Evaluation of Long-Term Survivorship Care for Cancer Patients in OECD Countries: A Systematic Review for Decision-Makers.International journal of environmental research and public health · 2021Pooled it
- A Meta-Analysis of Risk Factors for Transient and Permanent Hypocalcemia After Total Thyroidectomy.Frontiers in oncology · 2020Pooled it
- Thyroid carcinoma follow-up: tertiary to primary care transition in Portugal.Endocrine connections · 2026Article
- Morbidity profile and pharmaceutical management of adult outpatients between primary and tertiary care levels in Sri Lanka: a dual-centre, comparative study.BMC primary care · 2024Article
- Team-Based Care for Thyroid Cancer: What Is the Role of the Primary Care Physician?Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2024Article
- Real-World Cost-Effectiveness Analysis: How Much Uncertainty Is in the Results?Current oncology (Toronto, Ont.) · 2023Article
- Outcomes of Early Transition of Low-Risk Thyroid Cancer Patients from Specialist to Primary Care.Current oncology (Toronto, Ont.) · 2022Article
- Rapid Review of Real-World Cost-Effectiveness Analyses of Cancer Interventions in Canada.Current oncology (Toronto, Ont.) · 2022Review
- Hemithyroidectomy for Thyroid Cancer: A Review.Medicina (Kaunas, Lithuania) · 2020Review
- Treatment strategies for low-risk papillary thyroid carcinoma: a position statement from the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism (SBEM).Archives of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn unprecedented rise in the prevalence of low-risk well-differentiated thyroid cancer (TC) has been reported in several countries, which is partly due to an increased utility of sensitive imaging techniques. The outcome of these cancers has generally remained excellent and the overall 5-year survival is almost 100%. However, the extended follow-up strategy for these patients remains unclear and while the initial management is done in specialist centres some experts opt to follow them on a long-term basis while others discharge them to primary care after the initial management. The effectiveness of one strategy versus the other has not been studied.
methodsWe conducted a real-world comparison to assess the outcome of low-risk TC (AJCC stage I) with undetectable thyroglobulin (TG) 2 years after radio-iodine (I-131) therapy. The outcome from Halifax (NS, Canada) and London (ON, Canada), where all TC patients are routinely followed by the tertiary care team, was compared with that from Edmonton (AB, Canada), where patients are routinely discharged to primary care.
resultsAll patients were diagnosed between January 1, 2006, and December 31, 2011. The mean follow-up in primary care after discharge was 62.2 months and in tertiary care it was 64.6 months (
conclusionOur study shows that extended follow-up of low-risk TC patients is perfectly feasible in primary care and provides significant economic benefit for the healthcare system.
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Registered trials
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