ArticleTranslational vision science & technology2019
Assessing the Interocular Symmetry of Foveal Outer Nuclear Layer Thickness in Achromatopsia.
Article in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Assessing the Relationship between Foveal Cone Density, Outer Nuclear Layer Thickness and Foveal Morphology.Ophthalmology science · 2026Article
- Longitudinal Imaging of the Foveal Cone Mosaic in CNGA3-Associated Achromatopsia.Investigative ophthalmology & visual science · 2024Article
- Longitudinal Assessment of OCT-Based Measures of Foveal Cone Structure in Achromatopsia.Investigative ophthalmology & visual science · 2024Article
- Novel disease-causing variant inThe British journal of ophthalmology · 2022Article
- Longitudinal Evaluation of Changes in Retinal Architecture Using Optical Coherence Tomography in Achromatopsia.Investigative ophthalmology & visual science · 2022Article
- Long-term retinal imaging of a case of suspected congenital rubella infection.American journal of ophthalmology case reports · 2022Article
- KCNV2-Associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints-KCNV2 Study Group Report 2.American journal of ophthalmology · 2021Article
- Examining Whether AOSLO-Based Foveal Cone Metrics in Achromatopsia and Albinism Are Representative of Foveal Cone Structure.Translational vision science & technology · 2021Article
- Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia.Translational vision science & technology · 2021Article
- Sector Retinitis Pigmentosa: Extending the Molecular Genetics Basis and Elucidating the Natural History.American journal of ophthalmology · 2021Article
- Assessing Interocular Symmetry of the Foveal Cone Mosaic.Investigative ophthalmology & visual science · 2020Article
- Interocular Symmetry of Foveal Cone Topography in Congenital Achromatopsia.Current eye research · 2020Article
- Long-Term Investigation of Retinal Function in Patients with Achromatopsia.Investigative ophthalmology & visual science · 2020Article
- Preservation of the Foveal Avascular Zone in Achromatopsia Despite the Absence of a Fully Formed Pit.Investigative ophthalmology & visual science · 2020Article
- Assessing Intereye Symmetry and Its Implications for Study Design.Investigative ophthalmology & visual science · 2020Review
- Intraobserver Repeatability and Interobserver Reproducibility of Foveal Cone Density Measurements inTranslational vision science & technology · 2020Article
- Photoreceptor Structure in GNAT2-Associated Achromatopsia.Investigative ophthalmology & visual science · 2020Article
- Adaptive Optics Retinal Imaging in CNGA3-Associated Achromatopsia: Retinal Characterization, Interocular Symmetry, and Intrafamilial Variability.Investigative ophthalmology & visual science · 2019Article
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
9 authors.
Funding
Abstract
purposeWe examine the interocular symmetry of foveal outer nuclear layer (ONL) thickness measurements in subjects with achromatopsia (ACHM).
methodsImages from 76 subjects with
resultsMean (± standard deviation) foveal ONL thickness for subjects with ACHM was 79.7 ± 18.3 μm (right eye) and 79.2 ± 18.7 μm (left eye) compared to 112.9 ± 15.2 (right eye) and 112.1 ± 13.9 μm (left eye) for controls. Foveal ONL thickness did not differ between eyes for ACHM (
conclusionsWhile foveal ONL thickness is reduced in ACHM compared to controls, the high interocular symmetry indicates that contralateral ONL measurements could be used as a negative control in early-phase monocular treatment trials. TRANSLATIONAL RELEVANCE: Foveal ONL thickness can be measured using OCT images over a wide range of image quality. The interocular symmetry of foveal ONL thickness in ACHM and control populations supports the use of the non-study eye as a control for clinical trial purposes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.