Evidence map›Paper›PMID 31602310›Full record

ArticleNPJ biofilms and microbiomes

Blue laser light inhibits biofilm formation in vitro and in vivo by inducing oxidative stress.

Katia Rupel, Luisa Zupin, Giulia Ottaviani, Iris Bertani, Valentina Martinelli, Davide Porrelli, Simone Vodret, Roman Vuerich, Daniel Passos da Silva, Rossana Bussani and 6 more

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 74 citations in OpenAlex.

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  15. Inactivation of dried cells and biofilms ofApplied and environmental microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Katia Rupel1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-6150-9439
Luisa Zupin1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Giulia Ottaviani1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Iris Bertani2Bacteriology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.
Valentina Martinelli3Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.
Davide Porrelli1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-6437-7646
Simone Vodret3Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.
Roman Vuerich3Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.
Daniel Passos da Silva4Department of Microbiology, University of Washington, Seattle, WA 98195 USA.
Rossana Bussani1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Sergio Crovella1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Matthew Parsek4Department of Microbiology, University of Washington, Seattle, WA 98195 USA.
Vittorio Venturi2Bacteriology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), 34149 Trieste, Italy.
Roberto Di Lenarda1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Matteo Biasotto1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Serena Zacchigna1Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-6705-3076
University of Trieste · ITInternational Centre for Genetic Engineering and Biotechnology · ITUniversity of Washington · US

Funding

The pel exopolysaccharide gene cluster of Pseudomonas aeruginosaR01AI077628 · NIAID · UNIVERSITY OF WASHINGTON · PI MATTHEW R. PARSEK, Daniel J Wozniak · 2009 to 2026
$7.1M
NIAID NIH HHS R01 AI077628
6 · The paper itself

Abstract

Resolution of bacterial infections is often hampered by both resistance to conventional antibiotic therapy and hiding of bacterial cells inside biofilms, warranting the development of innovative therapeutic strategies. Here, we report the efficacy of blue laser light in eradicating

Indexed as

LasersLightOxidative StressAnimalsBiofilmsCell LineCulture MediaDisease Models, AnimalHumansMice, Inbred C57BLModels, BiologicalPseudomonas aeruginosaPseudomonas InfectionsRadiotherapyTreatment OutcomeWound InfectionCulture MediaBiofilmsDentistry

Identifiers

PMID31602310
PMCPMC6785554
OpenAlexW2980172753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.