Evidence map›Paper›PMID 31602277›Full record

ArticleJournal of Cancer2019

DNA methylation biomarkers in stool for early screening of colorectal cancer.

Jie Chen, Haipeng Sun, Weisen Tang, Lin Zhou, Xi Xie, Zhan Qu, Mengfei Chen, Shunyao Wang, Ting Yang, Ying Dai and 6 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04302363 (Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04302363 unknown statusnot on this map

Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer: a Study Protocol for Colorectal Neoplasms Screening

TypeobservationalSponsorWEIDONG LIU,MDRan2018 to 2021Enrolled500ConditionsGastrointestinal Microbiome, DNA Methylation, Colorectal NeoplasmsArmsFecal microbiota detection and exfoliated cell gene detection
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  3. Review
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  11. DNA methylation in necrotizing enterocolitis.Expert reviews in molecular medicine · 2024
    Review
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  13. Review
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Jie ChenDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Haipeng SunGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Weisen TangDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Lin ZhouDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Xi XieDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Zhan QuDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Mengfei ChenDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Shunyao WangGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Ting YangGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Ying DaiGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Yongli WangGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Tangjie GaoGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Qiao ZhouGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Zhuo SongGeneTalks Biotech Co., Ltd. Changsha, Hunan, 410000, P. R. China.
Mingmei LiaoKey Laboratory of Nanobiological Technology of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P.R. China.
Weidong LiuDepartment of Essential Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Sansure Biotech (China) · CNCentral South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkercolorectal cancerDNA methylationstool

Identifiers

PMID31602277
PMCPMC6775613
OpenAlexW2972416174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.