Evidence map›Paper›PMID 31602262›Full record

ArticleJournal of Cancer2019

Clinicopathologic and Prognostic Significance of Thymopoietin-α Overexpression in Gastric Cancer.

Ding-Ping Sun, Phui-Ly Liew, Chih-Chan Lin, Shih-Ting Hung, Tai-Chi Chen, Chia-Lang Fang, Kai-Yuan Lin

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ding-Ping SunDepartment of Surgery, Chi Mei Medical Center, Tainan, Taiwan.
Phui-Ly LiewDepartment of Pathology, Shuang Ho Hospital, Taipei Medical University, New Taipei, Taiwan.
Chih-Chan LinDepartment of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Shih-Ting HungDepartment of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Tai-Chi ChenDepartment of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Chia-Lang FangDepartment of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Kai-Yuan LinDepartment of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Chi Mei Medical Center · TWTaipei Medical University · TWChia Nan University of Pharmacy and Science · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As one of the deadliest and most common malignancies in the world, gastric cancer (GC) represents a serious health threat. Despite recent advances in the field, the prognosis of patients with metastatic GC remains poor. In this study, we aimed to investigate the clinical impact of the alpha subunit of the nuclear structural protein thymopoietin (TMPO-α) in GC. The expression of TMPO-α in seven gastric cell lines was detected by immunoblotting. The expression level of TMPO-α levels in gastric tissues collected from 145 GC patients was examined by immunohistochemistry. The correlations between TMPO-α expression level and clinicopathologic parameters, as well as the association of TMPO-α expression with overall survival, were assessed. Immunohistochemistry showed that the expression of TMPO-α was significantly higher in GC tissues and cells in comparison with non-tumor tissues and cells. Furthermore, the overexpression of TMPO-α in gastric tissues (56%) was positively associated with Lauren classification (

Indexed as

gastric cancerprognosis.TMPO-α

Identifiers

PMID31602262
PMCPMC6775605
OpenAlexW2972840929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.