Evidence map›Paper›PMID 31602223›Full record

ArticleExperimental and therapeutic medicine2019

Long non-coding RNA XIST promotes cell proliferation and migration through targeting miR-133a in bladder cancer.

Keqin Zhou, Jinrui Yang, Xurui Li, Wenjie Chen

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Bladder cancer: non-coding RNAs and exosomal non-coding RNAs.Functional & integrative genomics · 2024
    Review
  3. Article
  4. Article
  5. Potential roles of lncRNA-XIST/miRNAs/mRNAs in human cancer cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Long noncoding RNAGenes & diseases · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Long non-coding RNA XIST: a novel oncogene in multiple cancers.Molecular medicine (Cambridge, Mass.) · 2021
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Pyroptosis: mechanisms and diseases.Signal transduction and targeted therapy · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Keqin ZhouDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Jinrui YangDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Xurui LiDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Wenjie ChenDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long non-coding RNA (lncRNA) X inactive specific transcript (XIST) has recently been reported to promote the malignant progression of bladder cancer through regulating several microRNAs (miRs), including miR-124, miR-139-5p and miR-200c. However, whether other miRs are also involved in this process has remained to be determined. The present study demonstrated that XIST was significantly upregulated in bladder cancer tissues compared with that in adjacent normal tissues. Furthermore, its expression was reduced in several common bladder cancer cell lines. High expression of XIST was significantly associated with tumour progression and poor prognosis of patients with bladder cancer. An

Indexed as

bladder cancerlong non-coding RNAmicroRNAX inactive specific transcript

Identifiers

PMID31602223
PMCPMC6777290
OpenAlexW2970525177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.