Evidence map›Paper›PMID 31602169›Full record

SynthesisWorld journal of gastroenterology2019

Is there an association between

Qin Xiang Ng, Nadine Xinhui Foo, Wayren Loke, Yun Qing Koh, Vanessa Jing Min Seah, Alex Yu Sen Soh, Wee Song Yeo

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 6 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 6 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Medicina (Kaunas, Lithuania) · 2022
    Pooled it
  4. Pooled it
  5. The Association betweenInternational journal of environmental research and public health · 2020
    Pooled it
  6. Pooled it
  7. Review
  8. Article
  9. Article
  10. Factors associated with irritable bowel syndrome andThe Journal of international medical research · 2024
    Article
  11. Review
  12. Article
  13. No evidence for a causal link betweenFrontiers in microbiology · 2023
    Article
  14. Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia.Journal of neurogastroenterology and motility · 2021
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Qin Xiang NgMedicine, MOH Holdings Pte Ltd, Singapore 099253, Singapore.
Nadine Xinhui FooMedicine, MOH Holdings Pte Ltd, Singapore 099253, Singapore.
Wayren LokeMedicine, MOH Holdings Pte Ltd, Singapore 099253, Singapore.
Yun Qing KohMedicine, MOH Holdings Pte Ltd, Singapore 099253, Singapore.
Vanessa Jing Min SeahMedicine, MOH Holdings Pte Ltd, Singapore 099253, Singapore.
Alex Yu Sen SohDepartment of Gastroenterology and Hepatology, National University Hospital, National University Health System, Singapore 119074, Singapore.
Wee Song YeoYong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
MOH Holdings · SGNational University Hospital · SGTan Tock Seng Hospital · SGInstitute of Mental Health · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIrritable bowel syndrome (IBS) is a prevalent and debilitating gastrointestinal condition. Research has reported persistent, low-grade mucosal inflammation and significant overlaps between patients with IBS and those with dyspepsia, suggesting a possible pathogenic role of

aimTo investigate the association between

methodsUsing the keywords "

resultsA total of 13 clinical studies were systematically reviewed and nine studies were included in the final meta-analysis. Random-effects meta-analysis found a slight increased likelihood of

conclusionOverall, current evidence does not support an association between IBS and

Indexed as

Anti-Bacterial AgentsHelicobacter InfectionsHelicobacter pyloriHumansIrritable Bowel SyndromePrevalenceTreatment OutcomeAnti-Bacterial AgentsFunctionalHelicobacter pyloriInfectionIrritable bowel syndromeMeta-analysis

Identifiers

PMID31602169
PMCPMC6785524
OpenAlexW2975819899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.