ArticleScientific reports2019
Association of Microcalcification Clusters with Short-term Invasive Breast Cancer Risk and Breast Cancer Risk Factors.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- Elucidating cooperative genetic events in DCIS progression in mutantProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Breast microcalcifications as indicators of bone metastasis risk in early-stage breast cancer.Scientific reports · 2025Article
- Real-time peri-operative microcalcification detection in superficial breast tissues.Scientific reports · 2025Article
- Breast Cancer and Bone Mineral Density in a U.S. Cohort of Middle-Aged Women: Associations with Phosphate Toxicity.Cancers · 2023Article
- Development and CT image-domain validation of a computational lung lesion model for use in virtual imaging trials.Medical physics · 2023Article
- The effect of variable labels on deep learning models trained to predict breast density.Biomedical physics & engineering express · 2023Article
- Role of Secreted Frizzled-Related Protein 1 in Early Breast Carcinogenesis and Breast Cancer Aggressiveness.Cancers · 2023Article
- Microcalcifications, mammographic breast density, and risk of breast cancer: a cohort study.Breast cancer research : BCR · 2022Article
- Is loss of p53 a driver of ductal carcinoma in situ progression?British journal of cancer · 2022Review
- A 2,7-dichlorofluorescein derivative to monitor microcalcifications.Molecular systems design & engineering · 2022Article
- Cone-Beam Breast Computed Tomography: Time for a New Paradigm in Breast Imaging.Journal of clinical medicine · 2021Review
- Mammography features for early markers of aggressive breast cancer subtypes and tumor characteristics: A population-based cohort study.International journal of cancer · 2021Article
- Diabetes, Obesity, and Inflammation: Impact on Clinical and Radiographic Features of Breast Cancer.International journal of molecular sciences · 2021Review
- Predictors of mammographic microcalcifications.International journal of cancer · 2021Article
- Molecular Aspects and Prognostic Significance of Microcalcifications in Human Pathology: A Narrative Review.International journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Using for-presentation and for-processing digital mammograms, the presence of microcalcifications has been shown to be associated with short-term risk of breast cancer. In a previous article we developed an algorithm for microcalcification cluster detection from for-presentation digital mammograms. Here, we focus on digitised mammograms and use a three-step algorithm. In total, 253 incident invasive breast cancer cases (with a negative mammogram between three months and two years before diagnosis, from which we measured microcalcifications) and 728 controls (also with prior mammograms) were included in a short-term risk study. After adjusting for potential confounding variables, we found evidence of an association between the number of microcalcification clusters and short-term (within 3-24 months) invasive breast cancer risk (per cluster OR = 1.30, 95% CI = (1.11, 1.53)). Using the 728 postmenopausal healthy controls, we also examined association of microcalcification clusters with reproductive factors and other established breast cancer risk factors. Age was positively associated with the presence of microcalcification clusters (p = 4 × 10
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