ArticleCell research2019
Asymmetric distribution of cytokinins determines root hydrotropism in Arabidopsis thaliana.
Article in Cell research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- OsAux1 is required for nutritropism in rice roots.The Plant journal : for cell and molecular biology · 2026Article
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- Root system architecture and drought adaptation: emerging tools and genetic insights.Frontiers in plant science · 2026Review
- Root Meristem Maintenance Mechanisms are Key to Plant Defense Against Nanoplastics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Unearthing the hidden organ: vital role of the root in drought tolerance of plants.Plant molecular biology · 2025Review
- To grow or not to grow: the enigma of plant root growth dynamism.Plant molecular biology · 2025Review
- Foraging for water by MIZ1-mediated antagonism between root gravitropism and hydrotropism.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Roles of hormones in regulating root growth-water interactions.Journal of experimental botany · 2025Review
- A PIF-regulated switch in cell axis growth drives cotyledon expansion through tissue-specific cell expansion and division.The Plant journal : for cell and molecular biology · 2025Article
- Modulation of Root Hydrotropism and Recovery From Drought by MIZ1-like Genes in Tomato.Plant, cell & environment · 2025Article
- Arabidopsis calcium-dependent protein kinases 4/5/6/11 negatively regulate hydrotropism via phosphorylation of MIZU-KUSSEI1.The Plant cell · 2024Article
- Cytokinin-mediated enhancement of potato growth and yield by Verticillium Dahliae effector VDAL under low temperature stress.BMC plant biology · 2024Article
- Cytokinins regulate spatially specific ethylene production to control root growth in Arabidopsis.Plant communications · 2024Article
- Primary multistep phosphorelay activation comprises both cytokinin and abiotic stress responses: insights from comparative analysis of Brassica type-A response regulators.Journal of experimental botany · 2024Article
- Expression and functional divergence of a type-A response regulator paralog pair formed by dispersed duplication during Populus deltoides evolution.Communications biology · 2024Article
- Transcriptome Analysis of Rice Root Tips Reveals Auxin, Gibberellin and Ethylene Signaling Underlying Nutritropism.Plant & cell physiology · 2024Article
- Not so hidden anymore: Advances and challenges in understanding root growth under water deficits.The Plant cell · 2024Review
- Role of Abscisic Acid, Reactive Oxygen Species, and CaPlants (Basel, Switzerland) · 2024Review
- Long-term root electrotropism reveals habituation and hysteresis.Plant physiology · 2024Article
- Defects in the cell wall and its deposition caused by loss-of-function of three RLKs alter root hydrotropism in Arabidopsis thaliana.Nature communications · 2024Article
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11 authors.
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Abstract
The phenomenon of plant root tips sensing moisture gradient in soil and growing towards higher water potential is designated as root hydrotropism, which is critical for plants to survive when water is a limited factor. Molecular mechanisms regulating such a fundamental process, however, are largely unknown. Here we report our identification that cytokinins are key signaling molecules directing root growth orientation in a hydrostimulation (moisture gradient) condition. Lower water potential side of the root tip shows more cytokinin response relative to the higher water potential side. Consequently, two cytokinin downstream type-A response regulators, ARR16 and ARR17, were found to be up-regulated at the lower water potential side, causing increased cell division in the meristem zone, which allows the root to bend towards higher water potential side. Genetic analyses indicated that various cytokinin biosynthesis and signaling mutants, including the arr16 arr17 double mutant, are significantly less responsive to hydrostimulation. Consistently, treatments with chemical inhibitors interfering with either cytokinin biosynthesis or cell division completely abolished root hydrotropic response. Asymmetrically induced expression of ARR16 or ARR17 effectively led to root bending in both wild-type and miz1, a previously known hydrotropism-defective mutant. These data demonstrate that asymmetric cytokinin distribution is a primary determinant governing root hydrotropism.
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