Evidence map›Paper›PMID 31601909›Full record

ArticleScientific reports2019

Light-induced Nrf2

Kai Wang, Min Zheng, Kaitlyn Lee Lester, Zongchao Han

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Protective effects ofHistology and histopathology · 2026
    Article
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  10. Article
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  13. Modeling complex age-related eye disease.Progress in retinal and eye research · 2024
    Review
  14. Review
  15. Review
  16. Pegylated nanoceria: A versatile nanomaterial for noninvasive treatment of retinal diseases.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  17. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kai WangDepartment of Ophthalmology, the University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.ORCID http://orcid.org/0000-0002-4419-9598
Min ZhengDepartment of Ophthalmology, the University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Kaitlyn Lee LesterDepartment of Ophthalmology, the University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Zongchao HanDepartment of Ophthalmology, the University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. zongchao@med.unc.edu.ORCID http://orcid.org/0000-0002-2019-395X

Funding

Targeting Retinitis Pigmentosa Using Nanoparticle-Mediated Delivery of Genomic DNAR01EY026564 · NEI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAN, ZONGCHAO · 2016 to 2020
$1.9M
NEI NIH HHS R01 EY026564
6 · The paper itself

Abstract

Elevated oxidative stress and associated reactive oxygen species (ROS) accumulation are hallmarks in the induction and progression of age-related macular degeneration (AMD). By exposing nuclear factor erythroid 2-related factor (Nrf2) knockout (Nrf2

Indexed as

LightAnimalsAntioxidantsCeriumChitosanElectroretinographyFree RadicalsGene Expression RegulationGeographic AtrophyGlycolsHydrogelsInflammationMacular DegenerationMiceMice, Inbred C57BLMice, KnockoutAntioxidantsceric oxideCeriumChitosanFree RadicalsGlycolsHydrogelsNfe2l2 protein, mouseNF-E2-Related Factor 2Reactive Oxygen Species

Identifiers

PMID31601909
PMCPMC6787253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.