Evidence map›Paper›PMID 31601891›Full record

ArticleScientific reports2019

Morphological evidence for telocytes as stromal cells supporting satellite cell activation in eccentric contraction-induced skeletal muscle injury.

Mirko Manetti, Alessia Tani, Irene Rosa, Flaminia Chellini, Roberta Squecco, Eglantina Idrizaj, Sandra Zecchi-Orlandini, Lidia Ibba-Manneschi, Chiara Sassoli

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Telocytes of the male reproductive system: dynamic tissue organizers.Frontiers in cell and developmental biology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Telocytes: An Emerging Component of Stem Cell Niche Microenvironment.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Review
  16. Article
  17. Cd34+ Stromal Cells/Telocytes in Normal and Pathological Skin.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mirko ManettiDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy. mirko.manetti@unifi.it.ORCID http://orcid.org/0000-0003-3956-8480
Alessia TaniDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.
Irene RosaDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.
Flaminia ChelliniDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.
Roberta SqueccoDepartment of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy.
Eglantina IdrizajDepartment of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy.
Sandra Zecchi-OrlandiniDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.
Lidia Ibba-ManneschiDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.
Chiara SassoliDepartment of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy. chiara.sassoli@unifi.it.ORCID http://orcid.org/0000-0002-1337-0938
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although telocytes (TCs) have been proposed to play a "nursing" role in resident satellite cell (SC)-mediated skeletal muscle regeneration, currently there is no evidence of TC-SC morpho-functional interaction following tissue injury. Hence, we explored the presence of TCs and their relationship with SCs in an ex vivo model of eccentric contraction (EC)-induced muscle damage. EC-injured muscles showed structural/ultrastructural alterations and changes in electrophysiological sarcolemnic properties. TCs were identified in control and EC-injured muscles by either confocal immunofluorescence (i.e. CD34

Indexed as

Muscle ContractionAnimalsAntigens, CD34Basement MembraneMaleMiceMicroscopy, ConfocalMicroscopy, Electron, TransmissionMuscle DevelopmentMuscle, SkeletalMyoD ProteinPAX7 Transcription FactorRegenerative MedicineSatellite Cells, Skeletal MuscleStromal CellsTelocytesAntigens, CD34MyoD1 myogenic differentiation proteinMyoD ProteinPax7 protein, mousePAX7 Transcription Factor

Identifiers

PMID31601891
PMCPMC6787026
OpenAlexW2980133460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.