ArticleScientific reports2019
Association of oral health status with the CD4+ cell count in children living with HIV in Phnom Penh, Cambodia.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Impact of oral intervention on the oral and overall health of children living with HIV in Cambodia: a randomized controlled trial.BMC medicine · 2023Trial
- Dental caries in association with viral load in children living with HIV in Phnom Penh, Cambodia: a cross-sectional study.BMC oral health · 2021Trial
- Oral health among HIV-positive and HIV-negative children in Phnom Penh, Cambodia: a cross-sectional study.BMJ paediatrics open · 2021Trial
- Impact of perinatal HIV exposure and infection on salivary properties among Nigerian children.BMC oral health · 2024Article
- Age-specific associations with dental caries in HIV-infected, exposed but uninfected and HIV-unexposed uninfected children in Nigeria.BMC oral health · 2022Article
- Nutrition in HIV-Infected Infants and Children: Current Knowledge, Existing Challenges, and New Dietary Management Opportunities.Advances in nutrition (Bethesda, Md.) · 2021Review
- Oral health-related quality of life in patients infected with HIV, Iran: a cross-sectional study.BMC oral health · 2021Article
- Oral Health Status of Young People Infected with HIV in High Epidemic Area of China.Journal of multidisciplinary healthcare · 2021Article
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Authors and funding
6 authors.
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Abstract
The association between oral and overall health, and particularly between dental and immune health, in children living with HIV remains unclear. This study examined the association between the decayed, missing and filled teeth (DMFT) score and CD4+ cell counts in 142 children living with HIV aged 8-15 years (male, 51%) from Phnom Penh, Cambodia. Other indicators of oral health (e.g., debris index, salivary flow, salivary pH and oral health-related quality of life) and overall health (e.g., nutritional status and quality of life) were also evaluated. DMFT scores were negatively associated with the CD4+ cell count in male children (β: -0.13, 95% confidence interval [CI]: -0.25, -0.02). In all children, positive associations were observed between salivary pH and CD4+ count (β: -0.645, 95% CI: 0.02, 1.25) and between salivary flow and height-for-age Z-score (β: 1.22, 95% CI: 0.50, 1.95). The debris index was negatively associated with the height-for-age Z-score (β: -2.04, 95% CI: -3.38, -0.71). In summary, oral health was associated with immune and nutritional status. Oral health policies for children living with HIV should be emphasised, and further studies should evaluate the mechanism underlying the relationship between oral and overall health.
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