Evidence map›Paper›PMID 31601824›Full record

ArticleScientific reports2019

Utility of a Smartphone Based System (cvrPhone) to Predict Short-term Arrhythmia Susceptibility.

Kwanghyun Sohn, Steven P Dalvin, Faisal M Merchant, Kanchan Kulkarni, Furrukh Sana, Shady Abohashem, Jagmeet P Singh, E Kevin Heist, Chris Owen, Eric M Isselbacher and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. How to use digital devices to detect and manage arrhythmias: an EHRA practical guide.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022
    Article
  6. Utility of a Smartphone-Based System (cvrPhone) in Estimating Minute Ventilation from Electrocardiographic Signals.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2021
    Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kwanghyun SohnCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Steven P DalvinCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Faisal M MerchantCardiology Division, Emory, University School of Medicine, Atlanta, GA, USA.
Kanchan KulkarniCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-3185-0484
Furrukh SanaCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Shady AbohashemCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-5033-8881
Jagmeet P SinghCardiology Division, Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA.
E Kevin HeistCardiology Division, Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA.
Chris OwenNeurosurgery Division, Massachusetts General Hospital, Boston, MA, USA.
Eric M IsselbacherHealthcare Transformation Lab, Massachusetts General Hospital, Boston, MA, USA.
Antonis A ArmoundasCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. aarmoundas@partners.org.

Funding

Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
Prevention and Treatment of Ventricular TachyarrhythmiasR01HL135335 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2020
$2.1M
A Medical-Grade Smart-Phone Based Monitoring System (Supplement)R21EB026164 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2018 to 2020
$668k
Utility of Vagal Stimulation to Prevent the Onset of Ventricular ArrhythmiasR21HL137870 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2018
$468k
NCATS NIH HHS UL1 TR000170NHLBI NIH HHS R01 HL135335NHLBI NIH HHS R21 HL137870NIBIB NIH HHS R21 EB026164
6 · The paper itself

Abstract

Repolarization alternans (RA) has been implicated in the pathogenesis of ventricular arrhythmias and sudden cardiac death. We developed a 12-lead, blue-tooth/Smart-Phone (Android) based electrocardiogram (ECG) acquisition and monitoring system (cvrPhone), and an application to estimate RA, in real-time. In in-vivo swine studies (N = 17), 12-lead ECG signals were recorded at baseline and following coronary artery occlusion. RA was estimated using the Fast Fourier Transform (FFT) method using a custom developed algorithm in JAVA. Underlying ischemia was detected using a custom developed ischemic index. RA from each lead showed a significant (p < 0.05) increase within 1 min of occlusion compared to baseline (n = 29). Following myocardial infarction, spontaneous ventricular tachycardia episodes (n = 4) were preceded by significant (p < 0.05) increase of RA prior to the onset of the tachy-arrhythmias. Similarly, the ischemic index exhibited a significant increase following myocardial infarction (p < 0.05) and preceding a tachy-arrhythmic event. In conclusion, RA can be effectively estimated using surface lead electrocardiograms by analyzing beat-to-beat variability in ECG morphology using a smartphone based platform. cvrPhone can be used to detect myocardial ischemia and arrhythmia susceptibility using a user-friendly, clinically acceptable, mobile platform.

Indexed as

Monitoring, PhysiologicSmartphoneAlgorithmsAnimalsArrhythmias, CardiacDeath, Sudden, CardiacDisease Models, AnimalElectrocardiographyHeart VentriclesHumansMyocardial InfarctionSwineTachycardia, Ventricular

Identifiers

PMID31601824
PMCPMC6787075

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.