ArticleNature communications2019
N
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 72 citations in OpenAlex.
- Disruption of methionine metabolism drives erythroid cell fate reprogramming by remodeling the H3K4me3 landscape.The Journal of clinical investigation · 2026Article
- RBM15 in leukemogenesis: an emerging regulator at the interface of RNA biology and hematopoiesis.Trends in cancer · 2026Review
- The N6-methyladenosine (mBritish journal of haematology · 2026Article
- IMP1 is a novel posttranscriptional regulator of early erythroid development and embryonic globin output.Blood advances · 2026Article
- Methyltransferase complex subunit METTL3 maintains genome stability of erythroid cells via MTHFD1-mediated nucleotide biosynthesis.The Journal of clinical investigation · 2026Article
- Integrated analysis of post-transcriptional regulations reveals insights into acute myeloid leukemia.Communications biology · 2025Article
- N6-methyladenosine regulation of mRNA translation is essential for early human erythropoiesis.bioRxiv : the preprint server for biology · 2025Article
- WTAP-mediated mScience China. Life sciences · 2025Article
- mCells · 2025Review
- BRD4 acts as a transcriptional repressor of RhoB to inhibit terminal erythropoiesis.Journal of hematology & oncology · 2025Article
- Single-Cell Transcriptomic Analysis of the Potential Mechanisms of Follicular Development inInternational journal of molecular sciences · 2025Article
- The Oncogenic Role of UBXN1 in Gastric Cancer Is Attributed to the METTL16-Mediated m6A Methylation and Histone Modifications.Cancer medicine · 2025Article
- CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis.Genome biology · 2025Article
- Exploring the methyl-verse: Dynamic interplay of epigenome and m6A epitranscriptome.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Review
- Statistical modeling of immunoprecipitation efficiency of MeRIP-seq data enabled accurate detection and quantification of epitranscriptome.Computational and structural biotechnology journal · 2025Article
- RBM15-dependent m6A modification mediates progression of non-small cell lung cancer cells.Molecular medicine (Cambridge, Mass.) · 2024Article
- Epigenetic regulation of megakaryopoiesis and platelet formation.Haematologica · 2024Review
- Role of RNA modifications in blood development and regeneration.Experimental hematology · 2024Review
- NFIC mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to represses malignant phenotype of non-small cell lung cancer cells.Cancer cell international · 2024Article
- METTL3 exerts synergistic effects on m6A methylation and histone modification to regulate the function of VGF in lung adenocarcinoma.Clinical epigenetics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 3 countries.
Daniel A KuppersHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Sonali AroraHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Yiting LimHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Andrea R LimHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Lucas M CarterHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Philip D CorrinHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Christopher L PlaisierSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, 85281, USA.ORCID http://orcid.org/0000-0003-3273-5717
Ryan BasomGenomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.ORCID http://orcid.org/0000-0001-6137-1807
Jeffrey J DelrowGenomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.ORCID http://orcid.org/0000-0003-1020-3154
Shiyan WangPrincess Margaret Cancer Centre/University Health Network, Toronto, ON, Canada.
Housheng Hansen HePrincess Margaret Cancer Centre/University Health Network, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-2898-3363
Beverly Torok-StorbClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Andrew C HsiehHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. ahsieh@fredhutch.org.
Patrick J PaddisonHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. paddison@fredhutch.org.
Fred Hutch Cancer Center · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAUniversity Health Network · CAArizona State University · USUniversity of Washington · US
Funding
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4MProgenitor Cell Biology Consortium Administrative Coordinating CenterU01HL099997 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI TERRIN, MICHAEL L · 2009 to 2015
$29.9MCORE--VECTOR PRODUCTIONP30DK056465 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BERNSTEIN, IRWIN D · 1999 to 2014
$14.9MStem Cell and Transplantation BiologyU54DK106829 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DEREK L STIREWALT · 2015 to 2026
$9.1MControlling Hematopoietic Lineage Commitment from ESC to PlateletsU01HL099993 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TOROK-STORB, BEVERLY J. · 2009 to 2015
$8.3MHormone signaling and translation control in advanced prostate cancerR37CA230617 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HSIEH, ANDREW CALEB · 2019 to 2025
$3.1MEpitranscriptomic control of erythropoiesisR01DK119270 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PADDISON, PATRICK · 2019 to 2022
$1.8MDefining the role of eIF4F in metastatic castration resistant prostate cancerK08CA175154 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HSIEH, ANDREW CALEB · 2013 to 2017
$890kFHCRC High-Performance Computing ClusterS10OD020069 · OD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KOOPERBERG, CHARLES L · 2015 to 2015
$600kNCI NIH HHS K08 CA175154NCI NIH HHS P30 CA015704NCI NIH HHS R37 CA230617NHLBI NIH HHS U01 HL099993NHLBI NIH HHS U01 HL099997NIDDK NIH HHS P30 DK056465NIDDK NIH HHS R01 DK119270NIDDK NIH HHS U54 DK106829NIH HHS S10 OD020069
Abstract
Many of the regulatory features governing erythrocyte specification, maturation, and associated disorders remain enigmatic. To identify new regulators of erythropoiesis, we utilize a functional genomic screen for genes affecting expression of the erythroid marker CD235a/GYPA. Among validating hits are genes coding for the N
Indexed as
Protein BiosynthesisAdenosineAntigens, CD34Bone Marrow CellsCell Cycle ProteinsCell Line, TumorCRISPR-Cas SystemsErythropoiesisGene Expression RegulationHistonesHumansKruppel-Like Transcription FactorsLeukemia, Erythroblastic, AcuteMethyltransferasesPromoter Regions, GeneticRegulonAdenosineAntigens, CD34Cell Cycle Proteinserythroid Kruppel-like factorhistone H3 trimethyl Lys4HistonesKruppel-Like Transcription FactorsMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, MessengerRNA Splicing FactorsWTAP protein, human
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.