Evidence map›Paper›PMID 31601770›Full record

ArticleScience (New York, N.Y.)2019

Shisa7 is a GABA

Wenyan Han, Jun Li, Kenneth A Pelkey, Saurabh Pandey, Xiumin Chen, Ya-Xian Wang, Kunwei Wu, Lihao Ge, Tianming Li, David Castellano and 6 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Proteostasis regulation of GABABiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Haploinsufficiency of GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Human mutations inFrontiers in molecular neuroscience · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Wenyan HanSynapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-0886-1430
Jun Li *Synapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-1044-3724
Kenneth A Pelkey *Cellular and Synaptic Neuroscience Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-9731-1336
Saurabh PandeySynapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-2340-4975
Xiumin ChenQueensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-5764-6705
Ya-Xian WangAdvanced Imaging Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.
Kunwei WuSynapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-4074-0567
Lihao GeSynaptic Transmission Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-3849-446X
Tianming LiSynapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-8591-8632
David CastellanoSynapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-3400-3720
Chengyu LiuTransgenetic Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-5136-9225
Ling-Gang WuSynaptic Transmission Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
Ronald S PetraliaAdvanced Imaging Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.
Joseph W LynchQueensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-1227-2252
Chris J McBainCellular and Synaptic Neuroscience Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-5909-0157
Wei LuSynapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. luw4@mail.nih.gov.ORCID 0000-0001-6668-8432
National Institutes of Health · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USThe University of Queensland · AUNational Heart Lung and Blood Institute · US

Funding

The regulation of synaptic transmission and neural circuit functionZIANS003136 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI LU, WEI · 2012 to 2025
$27.0M
Advanced Imaging CoreZICDC000081 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI WINKLER, DENNIS · 2012 to 2025
$17.4M
Intramural NIH HHS Z99 NS999999Intramural NIH HHS ZIA NS003136Intramural NIH HHS ZIC DC000081
6 · The paper itself

Abstract

The function and pharmacology of γ-aminobutyric acid type A receptors (GABA

Indexed as

Synaptic TransmissionAnimalsBehavior, AnimalCA1 Region, HippocampalCell MembraneDiazepamGABA ModulatorsHEK293 CellsHumansInhibitory Postsynaptic PotentialsInterneuronsKineticsMembrane ProteinsMiceMice, KnockoutNerve Tissue ProteinsDiazepamGABA ModulatorsMembrane ProteinsNerve Tissue ProteinsReceptors, GABA-AShisa7 protein, mouse

Identifiers

PMID31601770
PMCPMC7382361
OpenAlexW2980150274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.