ArticleScience (New York, N.Y.)2019
Migratory DCs activate TGF-β to precondition naïve CD8
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
131 citing papers in PubMed, 1 synthesis or guideline pooled it, 204 citations in OpenAlex.
- Tissue-Resident Memory T Cells in Skin Diseases: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Mechanosensing by T cells promotes a tissue-resident memory transcriptional program.Nature immunology · 2026Article
- CD8MedComm · 2026Review
- Human tissue-resident CD8 T cells contribute to trophoblast homeostasis in health and during acute inflammation.bioRxiv : the preprint server for biology · 2026Article
- Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation.Mucosal immunology · 2026Article
- Immunological mechanistic action of intravenous BCG-mediated protection against tuberculosis.Cellular and molecular life sciences : CMLS · 2026Review
- Hidden immune memory niches in inflammatory skin diseases.bioRxiv : the preprint server for biology · 2026Article
- Smad4 and Eomes converge on a shared transcriptional program associated with inflammatory CD8 T-cell differentiation.Frontiers in immunology · 2026Article
- Early sex-related transcriptional differences in CD8Frontiers in immunology · 2026Article
- Origins of CD8 tissue resident memory.Frontiers in immunology · 2026Review
- Spatial Treg niches and the therapeutic reprogramming of tumour tolerance in cancer.Frontiers in cell and developmental biology · 2026Review
- Article
- Activation and Long-Term Maintenance of Adaptive Immunity in the Central Nervous System: A Double-Edged Sword?CNS neuroscience & therapeutics · 2025Review
- Tissue-Resident Memory T Cells: Pioneering New Avenues in Cancer Immunotherapy.Cancer medicine · 2025Review
- Development of intestinal tissue-resident T cells in early-life mice before and after weaning.Scientific reports · 2025Article
- GPR25 promotes the formation of lung and liver tissue-resident memory CD8 T cells.Science immunology · 2025Article
- Integrin CD103 expression in naive CD8Immunity · 2025Article
- Amlodipine as an immunomodulator to enhance dendritic cell activation in cancer therapy with tumor-associated antigens.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Article
- Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways.Cell reports · 2025Article
- PD-1 is requisite for skin TNature immunology · 2025Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
19 authors at 5 institutions in 2 countries.
Vinidhra ManiCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-1689-8391
Shannon K BromleyCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-5400-896X
Tarmo ÄijöCenter for Computational Biology, Flatiron Institute, New York, NY, USA.ORCID 0000-0002-3008-4634
Rut Mora-BuchCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-0117-0007
Esteban CarrizosaCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.
Ross D WarnerCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-9394-0912
Moustafa HamzeCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-3117-1967
Debattama R SenImmunology Graduate Program, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0947-8284
Alexandra Y ChasseCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-7970-2053
Alina LorantBenaroya Research Institute, Seattle, WA, USA.ORCID 0000-0002-1201-1618
Jason W GriffithCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-8942-0380
Rod A RahimiCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-7929-2899
Craig P McEnteeLydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.ORCID 0000-0002-4762-7607
Kate L JeffreyHarvard Medical School, Boston, MA, USA.ORCID 0000-0001-5746-0153
Francesco MarangoniCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-2490-849X
Mark A TravisLydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Adam Lacy-HulbertBenaroya Research Institute, Seattle, WA, USA.
Andrew D LusterCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-9679-7912
Thorsten R MempelCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA. tmempel@mgh.harvard.edu.ORCID 0000-0001-8635-5424
Harvard University · USBenaroya Research InstituteMassachusetts General Hospital · USWellcome Centre for Cell-Matrix Research · GBFlatiron Health (United States) · US
Funding
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3MStrategies to Overcome Immune Resistance in Head and Neck CancersP01CA240239 · NCI · YALE UNIVERSITY · PI PITTET, MIKAEL · 2019 to 2023
$8.4MResearch Training in Rheumatology at Massachusetts General HospitalT32AR007258 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI ANDREW D LUSTER · 1986 to 2026
$6.9MLung-Resident Memory Th2 cells in Asthma - New Therapeutic TargetsR01AI040618 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LUSTER, ANDREW D · 1997 to 2022
$5.6MCancer Immunology Training GrantT32CA207021 · NCI · DANA-FARBER CANCER INST · PI WUCHERPFENNIG, KAI W · 2016 to 2020
$2.4MArgonaute proteins in the mammalian antiviral responseR01AI107087 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI JEFFREY, KATE LOUISA · 2014 to 2018
$2.2MMechanisms of CD49a Expression and Resident Memory T Cell Formation in Skin.R01AI121546 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BROMLEY, SHANNON K · 2016 to 2020
$2.1MDistinct Function and Control of Regulatory T Cell Subsets During InfluenzaK08AI125816 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI GRIFFITH, JASON W. · 2017 to 2021
$1.1MThe Role of Lung-Resident Memory Th2 cells in AsthmaK08HL140173 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI RAHIMI, ROD AMIR · 2018 to 2022
$866kVisualizing the signals that drive resident memory T cell formation in skinR21AR070981 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI MEMPEL, THORSTEN ROMAN · 2017 to 2018
$403kBiotechnology and Biological Sciences Research Council BB/R003114/1NCI NIH HHS P01 CA240239NCI NIH HHS T32 CA207021NHLBI NIH HHS K08 HL140173NIAID NIH HHS K08 AI125816NIAID NIH HHS R01 AI040618NIAID NIH HHS R01 AI107087NIAID NIH HHS R01 AI121546NIAMS NIH HHS R21 AR070981NIAMS NIH HHS T32 AR007258NIDDK NIH HHS P30 DK043351Wellcome Trust
Abstract
Epithelial resident memory T (eT
Indexed as
Immunologic MemoryAnimalsCD8-Positive T-LymphocytesCell MovementDendritic CellsEpidermisIntegrin alphaVLymph NodesMiceMice, Inbred C57BLMice, TransgenicSkinTransforming Growth Factor betaIntegrin alphaVTransforming Growth Factor beta
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.