Evidence map›Paper›PMID 31601695›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

PET Imaging of Pancreatic Dopamine D

Jason Bini, Elizabeth Sanchez-Rangel, Jean-Dominique Gallezot, Mika Naganawa, Nabeel Nabulsi, Keunpoong Lim, Soheila Najafzadeh, Anupama Shirali, Jim Ropchan, David Matuskey and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Molecular connectivity studies in neurotransmission: a scoping review.Imaging neuroscience (Cambridge, Mass.) · 2025
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4 · The record

Corrections and comments

  • Commented on by
    2020
  • Commented on by
    Reply:2020
5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Jason BiniPET Center, Yale University School of Medicine, New Haven, Connecticut jason.bini@yale.edu.
Elizabeth Sanchez-RangelDepartment of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and.
Jean-Dominique GallezotPET Center, Yale University School of Medicine, New Haven, Connecticut.
Mika NaganawaPET Center, Yale University School of Medicine, New Haven, Connecticut.
Nabeel NabulsiPET Center, Yale University School of Medicine, New Haven, Connecticut.
Keunpoong LimPET Center, Yale University School of Medicine, New Haven, Connecticut.
Soheila NajafzadehPET Center, Yale University School of Medicine, New Haven, Connecticut.
Anupama ShiraliPET Center, Yale University School of Medicine, New Haven, Connecticut.
Jim RopchanPET Center, Yale University School of Medicine, New Haven, Connecticut.
David MatuskeyPET Center, Yale University School of Medicine, New Haven, Connecticut.
Yiyun HuangPET Center, Yale University School of Medicine, New Haven, Connecticut.
Kevan C HeroldDepartment of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and.
Paul E HarrisDepartment of Medicine, Division of Endocrinology, Columbia University, New York, New York.
Robert S SherwinDepartment of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and.
Richard E CarsonPET Center, Yale University School of Medicine, New Haven, Connecticut.
Gary W ClineDepartment of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and.
Yale University · USColumbia University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI WILLIAM V TAMBORLANE · 1993 to 2026
$44.0M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
State-of-the-Art PET/CT InstrumentationS10RR029245 · NCRR · YALE UNIVERSITY · PI CARSON, RICHARD E. · 2010 to 2010
$2.3M
Imaging pancreatic beta-cells with PET neuroimaging agentsDP3DK104092 · NIDDK · YALE UNIVERSITY · PI CARSON, RICHARD E., CLINE, GARY W · 2014 to 2016
$732k
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001863NCRR NIH HHS S10 RR029245NIDDK NIH HHS DP3 DK104092NIDDK NIH HHS P30 DK045735
6 · The paper itself

Abstract

Type 1 diabetes mellitus (T1DM) has traditionally been characterized by a complete destruction of β-cell mass (BCM); however, there is growing evidence of possible residual BCM present in T1DM. Given the absence of in vivo tools to measure BCM, routine clinical measures of β-cell function (e.g., C-peptide release) may not reflect BCM. We previously demonstrated the potential utility of PET imaging with the dopamine D

Indexed as

OxazinesPositron-Emission TomographyAdultDiabetes Mellitus, Type 1FemaleHumansLigandsMaleMiddle AgedPancreasReceptors, Dopamine D2Receptors, Dopamine D3Young AdultLigandsnaxagolideOxazinesReceptors, Dopamine D2Receptors, Dopamine D3diabetespancreasPETPHNOβ-cell mass

Identifiers

PMID31601695
PMCPMC7198375
OpenAlexW2979457666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.