Evidence map›Paper›PMID 31601686›Full record

ArticleHaematologica2020

Association of uric acid levels before start of conditioning with mortality after allogeneic hematopoietic stem cell transplantation - a prospective, non-interventional study of the EBMT Transplant Complication Working Party.

Olaf Penack, Christophe Peczynski, Steffie van der Werf, Jürgen Finke, Arnold Ganser, Helene Schoemans, Jiri Pavlu, Riitta Niittyvuopio, Wilfried Schroyens, Leylagül Kaynar and 14 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. The Impact of NLRP3 Activation on Hematopoietic Stem Cell Transplantation.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 11 countries.

Olaf PenackCharité Universitätsmedizin Berlin, Berlin, Germany.
Christophe PeczynskiEBMT Statistical Unit, Paris, France.
Steffie van der WerfEBMT Data Office, Leiden, the Netherlands.
Jürgen FinkeUniversity of Freiburg, Freiburg, Germany.
Arnold GanserHannover Medical School, Hannover, Germany.
Helene SchoemansDepartment of Hematology, University Hospital Leuven and KU Leuven, Leuven, Belgium.
Jiri PavluImperial College, London, UK.
Riitta NiittyvuopioHUCH Comprehensive Cancer Center, Helsinki, Finland.
Wilfried SchroyensAntwerp University Hospital, Antwerp, Belgium.
Leylagül KaynarErciyes University Medical Faculty, Kayseri, Turkey.
Igor W BlauCharité Universitätsmedizin Berlin, Berlin, Germany.
Walter van der VeldenRadboud University - Nijmegen Medical Centre, Nijmegen, the Netherlands.
Jorge SierraHospital Santa Creu I Sant Pau, Barcelona, Spain.
Agostino CortelezziFondazione IRCCS - Ca'Granda, Milan, Italy.
Gerald WulfUniversitätsklinikum Göttingen, Göttingen, Germany.
Pascal TurlureCHRU Limoges, Limoges, France.
Montserat RoviraHospital Clinic, Barcelona, Spain.
Zubeydenur OzkurtGazi University Faculty of Medicine, Ankara, Turkey.
Maria J Pascual-CasconHospital Regional de Málaga, Malaga, Spain.
Maria C MoreiraInstituto National do Cancer, Rio de Janeiro, Brazil.
Johannes ClausenElisabethinen-Hospital, Linz, Austria.
Hildegard GreinixLKH - University Hospital Graz, Graz, Austria.
Rafael F DuarteHospital Universitario Puerta de Hierro, Madrid, Spain.
Grzegorz W BasakMedical University of Warsaw, Warsaw, Poland.
Charité - Universitätsmedizin Berlin · DEAntwerp University Hospital · BECentre Hospitalier Universitaire de Limoges · FRErciyes University · TREuropean Society for Blood and Marrow Transplantation · FREuropean Society for Blood and Marrow Transplantation · NLFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITGazi University · TRGraz University Hospital · ATHospital Clínic de Barcelona · ESHospital de Sant Pau · ESHospital Regional Universitario de Málaga · ESHospital Universitario Puerta de Hierro Majadahonda · ESImperial College London · GBInstituto Nacional do Câncer · BRKrankenhaus der Elisabethinen · ATKU Leuven · BEMedical University of Warsaw · PLMedizinische Hochschule Hannover · DERadboud University Nijmegen · NL

Funding

Department of Health
6 · The paper itself

Abstract

Uric acid is a danger signal contributing to inflammation. Its relevance to allogeneic stem cell transplantation (alloSCT) derives from preclinical models where the depletion of uric acid led to improved survival and reduced graft-

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansProspective StudiesRetrospective StudiesTransplantation ConditioningTransplantation, HomologousUric AcidUric Acid

Identifiers

PMID31601686
PMCPMC7327652
OpenAlexW2979879573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.