ArticleThe Journal of biological chemistry2019
FOXO1 transcription factor regulates chondrogenic differentiation through transforming growth factor β1 signaling.
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Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
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Who cites it
44 citing papers in PubMed, 65 citations in OpenAlex.
- UCHL1 enhancesHistology and histopathology · 2026Article
- FOXI3 establishes the ectodermal niche in pharyngeal arches for cranial neural crest cells and their lineages.Bone research · 2026Article
- FOXO1 Inhibition and FADD Knockdown Have Opposing Effects on Anticancer Drug-Induced Cytotoxicity and p21 Expression in Osteosarcoma Cells.International journal of molecular sciences · 2026Article
- A proteomics investigation of primary human articular chondrocyte isolation.Osteoarthritis and cartilage open · 2025Article
- FoxO1 signaling in B cell malignancies and its therapeutic targeting.FEBS letters · 2025Review
- Forkhead box O proteins in chondrocyte aging and diseases.Journal of orthopaedic translation · 2025Review
- TRIM47 promotes the Warburg effect and reduces ferroptosis in prostate cancer by FBP1 and FOXO1.Translational andrology and urology · 2024Article
- Protein phosphatase SCP4 regulates cartilage development and endochondral osteogenesis via FoxO3a dephosphorylation.Cell proliferation · 2024Article
- Forkhead box O proteins: steering the course of stem cell fate.Cell regeneration (London, England) · 2024Review
- In silico and in vitro analyses of a novel FoxO1 agonist reducing Aβ levels via downregulation of BACE1.CNS neuroscience & therapeutics · 2024Article
- Inhibition of HOXD11 promotes cartilage degradation and induces osteoarthritis development.Journal of orthopaedic surgery and research · 2024Article
- Bioinformatics Analysis and Experimental Validation of Mitochondrial Autophagy Genes in Knee Osteoarthritis.International journal of general medicine · 2024Article
- Engineering mesenchymal stem cells for premature ovarian failure: overcoming challenges and innovating therapeutic strategies.Theranostics · 2024Review
- Mild Intermittent Cold Stimulation Affects Cardiac Substance Metabolism via the Neuroendocrine Pathway in Broilers.Animals : an open access journal from MDPI · 2023Article
- Article
- Wedelolactone Promotes the Chondrogenic Differentiation of Mesenchymal Stem Cells by Suppressing EZH2.International journal of stem cells · 2023Article
- FOXO1 regulates osteogenic differentiation of periodontal ligament stem cells through the METTL3 signaling pathway.Journal of orthopaedic surgery and research · 2023Article
- Lysine 68 Methylation-Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Apoptosis Related Human Wharton's Jelly-Derived Stem Cells Differentiation into Osteoblasts, Chondrocytes, Adipocytes and Neural-like Cells-Complete Transcriptomic Assays.International journal of molecular sciences · 2023Article
- AKBA inhibits radiotherapy resistance in lung cancer by inhibiting maspin methylation and regulating the AKT/FOXO1/p21 axis.Journal of radiation research · 2023Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Ichiro KurakazuDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Yukio AkasakiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan akasaki@ortho.med.kyushu-u.ac.jp.
Mitsumasa HayashidaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Hidetoshi TsushimaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Norio GotoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Takuya SueishiDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Masakazu ToyaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Masanari KuwaharaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Ken OkazakiDepartment of Orthopaedic Surgery, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Tomas DuffyDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037.
Martin K LotzDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037.
Yasuharu NakashimaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, Fukuoka 812-8582, Japan.
Kyushu University · JPScripps Research Institute · USTokyo Women's Medical University · JP
Funding
FoxO transcription factors in joint aging and osteoarthritis pathogenesisR37AG059418 · NIA · SCRIPPS RESEARCH INSTITUTE, THE · PI Martin K Lotz · 2018 to 2026
$5.0MNIA NIH HHS R37 AG059418
Abstract
The forkhead box O (FOXO) proteins are transcription factors involved in the differentiation of many cell types.
Indexed as
AggrecansAnimalsCell Cycle CheckpointsCell DifferentiationChondrogenesisCollagen Type IICyclin-Dependent Kinase Inhibitor p21Forkhead Box Protein O1Gene Expression Regulation, DevelopmentalHumansMesenchymal Stem CellsMiceSmad ProteinsSOX9 Transcription FactorTransforming Growth Factor beta1ACAN protein, humanAggrecansCDKN1A protein, humanCOL2A1 protein, humanCollagen Type IICyclin-Dependent Kinase Inhibitor p21Forkhead Box Protein O1FOXO1 protein, humanSmad ProteinsSOX9 protein, humanSOX9 Transcription FactorTGFB1 protein, humanTransforming Growth Factor beta1cell cyclecell differentiationchondrocytecyclin dependent kinase inhibitor 1A (CDKN1A)FOXOp21sex-determining region Y box 9 (SOX9)SMAD transcription factorSRY-box 9transforming growth factor beta (TGF-B)
Identifiers
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.