Evidence map›Paper›PMID 31601602›Full record

Observational studyBMJ open2019

Comparing the predictive ability of a commercial artificial intelligence early warning system with physician judgement for clinical deterioration in hospitalised general internal medicine patients: a prospective observational study.

Jonathan Arnold, Alex Davis, Baruch Fischhoff, Emmanuelle Yecies, Jon Grace, Andrew Klobuka, Deepika Mohan, Janel Hanmer

Registry-linked trialOpen access · goldAbstract readComparative StudyObservational Study
In one paragraph

Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02648828 (Understanding Physician Signout Risk Perception), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02648828 completednot on this map

Understanding Physician Signout Risk Perception

TypeobservationalSponsorUniversity of PittsburghRan2015 to 2016Enrolled132ConditionsPhysician JudgmentArmsClinical deterioration
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Assessing Risk of Early ICU Admission or Death at Emergency Department Triage: Clinical Judgment Versus Early Warning Scores.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jonathan ArnoldDivision of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA arnoldjd@pitt.edu.ORCID 0000-0003-1185-555X
Alex DavisEngineering and Public Policy, Carnegie Mellon University College of Engineering, Pittsburgh, Pennsylvania, USA.
Baruch FischhoffEngineering and Public Policy, Carnegie Mellon University College of Engineering, Pittsburgh, Pennsylvania, USA.
Emmanuelle YeciesDivision of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Jon GraceDivision of Pulmonary & Critical Care Medicine, University of Michigan Department of Internal Medicine, Ann Arbor, Michigan, USA.
Andrew KlobukaDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Deepika MohanDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Janel HanmerDivision of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · USCarnegie Mellon University · USMichigan Medicine · US

Funding

Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
NCATS NIH HHS KL2 TR001856
6 · The paper itself

Abstract

objectiveOur study compares physician judgement with an automated early warning system (EWS) for predicting clinical deterioration of hospitalised general internal medicine patients.

designProspective observational study of clinical predictions made at the end of the daytime work-shift for an academic general internal medicine floor team compared with the risk assessment from an automated EWS collected at the same time.

settingInternal medicine teaching wards at a single tertiary care academic medical centre in the USA.

participantsIntern physicians working on the internal medicine wards and an automated EWS (Rothman Index by PeraHealth). OUTCOME: Clinical deterioration within 24 hours including cardiac or pulmonary arrest, rapid response team activation or unscheduled intensive care unit transfer.

resultsWe collected predictions for 1874 patient days and saw 35 clinical deteriorations (1.9%). The area under the receiver operating curve (AUROC) for the EWS was 0.73 vs 0.70 for physicians (p=0.571). A linear regression model combining physician and EWS predictions had an AUROC of 0.75, outperforming physicians (p=0.016) and the EWS (p=0.05).

conclusionsThere is no significant difference in the performance of the EWS and physicians in predicting clinical deterioration at 24 hours on an inpatient general medicine ward. A combined model outperformed either alone. The EWS and physicians identify partially overlapping sets of at-risk patients suggesting they rely on different cues or decision rules for their predictions. TRIAL REGISTRATION NUMBER: NCT02648828.

Indexed as

Artificial IntelligenceClinical CompetenceClinical DeteriorationAdultAgedAlgorithmsEarly Warning ScoreFemaleHospitalizationHumansInternal MedicineJudgmentMaleMiddle AgedPhysiciansProspective Studiesclinicalclinical decision-makingclinical deteriorationdecision support systemsearly warning systemshealth information systems

Identifiers

PMID31601602
PMCPMC6797436
OpenAlexW2979476673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.