Evidence map›Paper›PMID 31601551›Full record

ArticleBMJ case reports2019

A case of sporadic erythromelalgia presenting with small fibre neuropathy.

Pavan Patel, Yan Zhang, Lynne H Unikel, Christopher Edwards

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pavan PatelNeurology, Albert Einstein Medical Center, Philadelphia, PA, USA Patelpav@einstein.edu.ORCID http://orcid.org/0000-0002-7387-2083
Yan ZhangNeurology, Albert Einstein Medical Center, Philadelphia, PA, USA.
Lynne H UnikelNeurology, Albert Einstein Medical Center, Philadelphia, PA, USA.
Christopher EdwardsNeurology, Albert Einstein Medical Center, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erythromelalgia (EM) is a rare disorder of small nerve fibres that leads to painful flushing and burning paresthesisas of the distal extremities and is typically associated with heat or physical activity; relief is found using cooling measures. Its effects are often debilitating in the general population, but this patient had an excellent response to specific treatment options and continues to maintain employment, something many individuals suffering from EM are unable to do. His presentation was also unique in that he had isolated, proximal involvement as his condition progressed whereas typically only the distal extremities are affected. Routine electromyography and nerve conduction studies were normal, whereas nerve biopsy demonstrated findings of small fibre neuropathy. Ultimately, his condition was managed with carbamazepine and his symptoms have almost entirely resolved to date.

Indexed as

AdultAnalgesics, Non-NarcoticCarbamazepineDiagnosis, DifferentialElectromyographyErythromelalgiaHumansMaleNeural ConductionSmall Fiber NeuropathyTreatment OutcomeAnalgesics, Non-NarcoticCarbamazepineneuro geneticsneurologypain (neurology)

Identifiers

PMID31601551
PMCPMC6803085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.