Evidence map›Paper›PMID 31601379›Full record

ReviewJACC. Cardiovascular imaging2019

Structural and Physiological Imaging to Predict the Risk of Lethal Ventricular Arrhythmias and Sudden Death.

Saurabh Malhotra, John M Canty

Open access · greenAbstract readReview
In one paragraph

Review in JACC. Cardiovascular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Detection of myocardial fibrosis: Where we stand.Frontiers in cardiovascular medicine · 2022
    Review
  3. Review
  4. Global and regional cardiac dysfunction quantified byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Saurabh MalhotraDivision of Cardiology, Cook County Health and Division of Cardiology, Rush Medical College, Chicago, Illinois.
John M CantyDepartments of Medicine, Biomedical Engineering and Physiology and Biophysics, the Department of Veterans Affairs Western New York Health Care System and the Clinical and Translational Research Center at the University at Buffalo, Buffalo, New York. Electronic address: canty@buffalo.edu.
Rush University Medical Center · USVA Western New York Healthcare System · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Metabolic Adaptation and Functional Recovery of Hibernating MyocardiumR01HL061610 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 2000 to 2018
$6.0M
PAREPET II_Prediction of ARrhythnic Events with Positron Emission Tomography IIR01HL130266 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M, FALLAVOLLITA, JAMES · 2016 to 2022
$3.6M
Preventing and Reversing Interstitial Fibrosis in HFpEFI01BX002659 · VA · VA WESTERN NEW YORK HEALTHCARE SYSTEM · PI Brian Raymond Weil · 2016 to 2026
–
BLRD VA I01 BX002659NCATS NIH HHS UL1 TR001412NHLBI NIH HHS R01 HL061610NHLBI NIH HHS R01 HL130266
6 · The paper itself

Abstract

Identifying patients at risk of sudden cardiac death remains a major challenge in cardiovascular medicine. Advances in cardiovascular imaging have identified several anatomic and functional variables that can be quantified as continuous variables to predict the risk of developing lethal ventricular tachyarrhythmias in patients with depressed left ventricular (LV) systolic function. Some, such as LV mass, volume, and the dyssynchrony of contraction, can be derived from currently available echocardiographic and nuclear imaging modalities. Others require advanced cardiac imaging modalities with quantification of myocardial scar with gadolinium-enhanced cardiac magnetic resonance and myocardial sympathetic denervation using norepinephrine analogs and positron emission tomography or single-photon emission computed tomography offering the most promise. There is an immediate need to develop a sequential cost-effective approach that capitalizes on readily available clinical information complemented with advanced imaging modalities in selected patients to improve risk stratification for arrhythmic death beyond LV ejection fraction.

Indexed as

Cardiac Imaging TechniquesArrhythmias, CardiacDeath, Sudden, CardiacHumansPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsStroke VolumeVentricular Function, Leftcardiac imagingdyssynchronyimplantable cardioverter-defibrillatormyocardial fibrosissudden cardiac deathsympathetic innervation

Identifiers

PMID31601379
PMCPMC6800667
OpenAlexW2979898176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.