Evidence map›Paper›PMID 31601280›Full record

ArticleInfection control and hospital epidemiology2019

Association between chlorhexidine gluconate concentrations and resistant bacterial bioburden on skin.

Gita Nadimpalli, Lyndsay M O'Hara, Surbhi Leekha, David P Calfee, Loren G Miller, Lisa Pineles, Natalia Blanco, J Kristie Johnson, Anthony D Harris, CDC Prevention Epicenters Program

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection control and hospital epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gita NadimpalliDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0002-6283-1032
Lyndsay M O'HaraDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
Surbhi LeekhaDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
David P CalfeeDivision of Infectious Diseases, Weill Cornell Medicine, New York, New York.
Loren G MillerLA Biomedical Research Center at Harbor-UCLA Medical Center, Torrance, California.
Lisa PinelesDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
Natalia BlancoDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0002-3157-1119
J Kristie JohnsonDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
Anthony D HarrisDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
CDC Prevention Epicenters Program

Funding

Epidemiology of CRE and MRSA transmission: patient and organism factorsR01AI121146 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI HARRIS, ANTHONY D · 2016 to 2019
$2.5M
ACL HHS U54CK000450NCEZID CDC HHS U54 CK000450NIAID NIH HHS R01 AI121146
6 · The paper itself

Abstract

We studied the association between chlorhexidine gluconate (CHG) concentration on skin and resistant bacterial bioburden. CHG was almost always detected on the skin, and detection of methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, and vancomycin-resistant Enterococcus on skin sites was infrequent. However, we found no correlation between CHG concentration and bacterial bioburden.

Indexed as

Anti-Infective Agents, LocalChlorhexidineDose-Response Relationship, DrugDrug Resistance, BacterialHumansSkinAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconate

Identifiers

PMID31601280
PMCPMC6897301

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.