Evidence map›Paper›PMID 31601189›Full record

ArticleBMC geriatrics2019

Prevalence of Potentially Inappropriate Medication use in older drivers.

Guohua Li, Howard F Andrews, Stanford Chihuri, Barbara H Lang, Cheng Shiun Leu, David P Merle, Abigail Gordon, Thelma J Mielenz, David Strogatz, David W Eby and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  11. Evaluation of psychotropic medications use among elderly with psychiatric disorders in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Guohua LiDepartment of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, NY, USA. GL2240@cumc.columbia.edu.ORCID 0000-0003-4732-2448
Howard F AndrewsDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Stanford ChihuriDepartment of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Barbara H LangDepartment of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Cheng Shiun LeuDepartment of Biostatistics, Columbia University Mailman School of Public Health, New York, NY, USA.
David P MerleDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Abigail GordonDepartment of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Thelma J MielenzDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
David StrogatzBassett Research Institute, Cooperstown, NY, USA.
David W EbyUniversity of Michigan Transportation Research Institute, Ann Arbor, MI, USA.
Marian E BetzDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Carolyn DiGuiseppiDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Vanya C JonesDepartment of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Lisa J MolnarUniversity of Michigan Transportation Research Institute, Ann Arbor, MI, USA.
Linda L HillDepartment of Family and Preventive Medicine, University of California San Diego, La Jolla, CA, USA.
LongROAD Research Team
Columbia University · USColumbia University Irving Medical Center · USMichigan Department of Transportation · USBassett Medical Center · USColorado School of Public Health · USJohns Hopkins University · USUniversity of California San Diego · USUniversity of Colorado Denver · US

Funding

The Johns Hopkins Alzheimer's Disease Resource Center for Minority Aging Research - Research Ed ComponentP30AG059298 · NIA · JOHNS HOPKINS UNIVERSITY · PI Joseph John Gallo, ROLAND J. THORPE · 2018 to 2026
$7.1M
NIA NIH HHS P30 AG059298
6 · The paper itself

Abstract

backgroundPotentially Inappropriate Medication (PIM) use has been studied in a variety of older adult populations across the world. We sought to examine the prevalence and correlates of PIM use in older drivers.

methodsWe applied the American Geriatrics Society 2015 Beers Criteria to baseline data collected from the "brown-bag" review of medications for participants of the Longitudinal Research on Aging Drivers (LongROAD) study to examine the prevalence and correlates of PIM use in a geographically diverse, community-dwelling sample of older drivers (n = 2949). Proportions of participants who used one or more PIMs according to the American Geriatrics Society 2015 Beers Criteria, and estimated odds ratios (ORs) and 95% confidence intervals (CIs) of PIM use associated with participant characteristics were calculated.

resultsOverall, 18.5% of the older drivers studied used one or more PIM. The most commonly used therapeutic category of PIM was benzodiazepines (accounting for 16.6% of the total PIMs identified), followed by nonbenzodiazepine hypnotics (15.2%), antidepressants (15.2%), and first-generation antihistamines (10.5%). Compared to older drivers on four or fewer medications, the adjusted ORs of PIM use were 2.43 (95% CI 1.68-3.51) for those on 5-7 medications, 4.19 (95% CI 2.95-5.93) for those on 8-11 medications, and 8.01 (95% CI 5.71-11.23) for those on ≥12 medications. Older drivers who were female, white, or living in urban areas were at significantly heightened risk of PIM use.

conclusionAbout one in five older drivers uses PIMs. Commonly used PIMs are medications known to impair driving ability and increase crash risk. Implementation of evidence-based interventions to reduce PIM use in older drivers may confer both health and safety benefits.

trial registrationNot applicable.

Indexed as

Potentially Inappropriate Medication ListAgedAged, 80 and overAgingAutomobile DrivingCohort StudiesCross-Sectional StudiesFemaleGeriatricsHumansInappropriate PrescribingIndependent LivingLongitudinal StudiesMalePrevalenceProspective StudiesAgingBeers criteriaDriving safetyOlder adultsPotentially inappropriate medications

Identifiers

PMID31601189
PMCPMC6785868
OpenAlexW2979318031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.