ArticleBMC cardiovascular disorders2019
Going beyond classic echo in aortic stenosis: left atrial mechanics, a new marker of severity.
Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Prognostic Role of Left Atrial Reservoir Strain for Risk Stratification in Aortic Stenosis: A Systematic Review.Journal of clinical medicine · 2026Review
- Comprehensive Echocardiographic Assessment in Moderate Aortic Stenosis with Preserved Ejection Fraction Using Two-Dimensional Speckle-Tracking Echocardiography: Association with Functional Capacity.Journal of clinical medicine · 2025Article
- Impact of Aortic Stenosis Severity on Left Heart Function Analyzed Using CT-Derived Strain Parameters.Korean journal of radiology · 2025Article
- Incremental diagnostic and prognostic utility of left atrial deformation in heart failure using speckle tracking echocardiography.Heart failure reviews · 2024Review
- Severe aortic stenosis detection by deep learning applied to echocardiography.European heart journal · 2023Article
- Interaction between the left ventricular ejection fraction and left ventricular strain and its relationship with coronary stenosis.World journal of clinical cases · 2023Article
- Left atrial function index (LAFI) and outcome in patients undergoing transcatheter aortic valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- Cardiovascular outcomes in patients with left atrial enlargement undergoing transcatheter aortic valve implantation.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022Article
- The effects of cardiac stretch on atrial fibroblasts: analysis of the evidence and potential role in atrial fibrillation.Cardiovascular research · 2022Review
- Aortic strain in bicuspid aortic valve: an analysis.The international journal of cardiovascular imaging · 2021Article
- Incremental prognostic role of left atrial reservoir strain in asymptomatic patients with moderate aortic stenosis.The international journal of cardiovascular imaging · 2021Article
- Review: application of current imaging modalities in the management of left-sided valvular heart disease.Cardiovascular diagnosis and therapy · 2021Review
- Left atrial functional assessment and mortality in patients with severe aortic stenosis with sinus rhythm.Cardiovascular ultrasound · 2021Article
- Cardiac Imaging for the Assessment of Left Atrial Mechanics Across Heart Failure Stages.Frontiers in cardiovascular medicine · 2021Review
- The Central Role of Left Atrium in Heart Failure.Frontiers in cardiovascular medicine · 2021Review
- Potential Diagnostic and Prognostic Values of Left Atrial Strain in Valvular Heart Disease.Journal of cardiovascular echographyReview
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited information regarding left atrial (LA) mechanics in aortic valve stenosis (AS). We assessed LA mechanics in AS through speckle-tracking echocardiography (STE) according to severity and prognosis.
methodsWe included 102 patients diagnosed with severe AS (sAS) and 80 patients with moderate AS (mAS), all with preserved ejection fraction and no coronary artery disease. LA mechanics and left ventricular global longitudinal strain (LV-GLS) were assessed by STE. The cohort was followed-up for a median of 30 (IQR 12.6-50) months, and outcomes were determined (combined outcome of HF, death, and aortic valve replacement).
resultsIn our sample set, values of LV-GLS (- 18.5% vs - 17.1, p = 0.025), E/e' ratio (15.8 vs 18.4, p = 0.03), and global LA mechanics (LA ɛsys, 23% vs 13.8%, p < 0.001) were worse for sAS compared to those for mAS. However, LA ɛsys (AUC 0.85, 95% CI 0.78-0.90, p < 0.001), ɛe (AUC 0.83, 95% CI 0.75-0.88, p < 0.001), and ɛa (AUC 0.80, 95% CI 0.70-0.84, p < 0.001) were the best discriminators of sAS, with sensitivities higher than 85%. LA ɛsys showed a stronger correlation with both aortic valve area (r
conclusionsLA global strain was the best discriminator of severity, surpassing E/e' ratio and LV-GLS, and a significant predictor of prognosis in AS.
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