Evidence map›Paper›PMID 31601110›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2019

Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family.

Sun Kyung Kim, Morkos A Henen, Andrew P Hinck

Abstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
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  14. Cripto-1 acts as a molecular bridge linking nodal to ALK4 via distinct structural domains.Protein science : a publication of the Protein Society · 2025
    Article
  15. Review
  16. Review
  17. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sun Kyung KimDepartment of Structural Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Morkos A HenenDepartment of Structural Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0003-4835-5583
Andrew P HinckDepartment of Structural Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0003-3320-8054

Funding

LIGAND/RECEPTOR INTERACTIONS IN THE TGF BETA SUPERFAMILYR01GM058670 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HINCK, ANDREW P · 1999 to 2017
$3.6M
HTS for TGF-beta receptor assembly inhibitors with anti-tumor and anti-fibrosis activitiesR01CA233622 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HINCK, ANDREW P, JOHNSTON, PAUL A. · 2019 to 2022
$2.0M
Inhibition of the tumor-promoting effects of TGF-beta in advanced prostate cancerR01CA172886 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HINCK, ANDREW P, SUN, LUZHE · 2013 to 2016
$1.2M
NCI NIH HHS R01 CA172886NCI NIH HHS R01 CA233622NIGMS NIH HHS R01 GM058670
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsEndoglinHumansMembrane ProteinsProtein BindingProteoglycansReceptors, Transforming Growth Factor betaSignal TransductionTransforming Growth Factor betabetaglycanEndoglinMembrane ProteinsProteoglycansReceptors, Transforming Growth Factor betaTransforming Growth Factor betabetaglycancell signalingco-receptorendoglinStructural biologyTGF-betatransforming growth factor-beta

Identifiers

PMID31601110
PMCPMC6920675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.