Evidence map›Paper›PMID 31601055›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis of Novel Baicalein Amino Acid Derivatives and Biological Evaluation as Neuroprotective Agents.

Xiaohui Jia, Menglu Jia, Yuqin Yang, Di Wang, Fei Zhou, Wenxi Zhang, Xuemei Huang, Wenbo Guo, Desheng Cai, Hongshan Chen and 7 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Novel Baicalein-Derived Inhibitors ofPathogens (Basel, Switzerland) · 2023
    Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Xiaohui JiaSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. 18811508865@163.com.
Menglu JiaBeijing Shijingshan District Medical Security Bureau, 66 Yangzhuang Road, Shijingshan, Beijing 100043, China. 15001290933@163.com.
Yuqin YangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. yangyq5@163.com.
Di WangFuxin Health School, Liaoning 123000, China. Diven0804@163.com.
Fei ZhouSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. zf116318@163.com.
Wenxi ZhangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. zhangwxnn@126.com.
Xuemei HuangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. hxm3928@163.com.
Wenbo GuoSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. wb_guo@126.com.
Desheng CaiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. cai1225366978@163.com.
Hongshan ChenSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. chs1314as@163.com.
Jinchai QiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. 17862969559@163.com.
Shuqi ZhouSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China.
Haomiao RenSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. 18811189872@163.com.
Bing XuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. xubing@126.com.
Tao MaSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. mosesmatao@163.com.
Penglong WangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. wpl581@126.com.
Haimin LeiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. hm_lei@126.com.ORCID 0000-0001-6765-9545
Beijing University of Chinese Medicine · CNBeijing Shijingshan Hospital · CN

Funding

China Association of C22hinese Medicine CACM-2018-QNRC2-B08Fundamental Research Funds for the Central Universities 2019-JYB-TD005Fundamental Research Funds for the Central Universities BUCM-2018-2020Fundamental Research Funds for the Central Universities BUCM-2019-JCRC002National Natural Science Foundation of China 81603256
6 · The paper itself

Abstract

Baicalein, a famously effective component of the traditional Chinese medicine Rhizoma Huang Qin (

Indexed as

Amino AcidsAngiogenesis Inducing AgentsAnimalsApoptosisCell Line, TumorCell SurvivalChemistry Techniques, SyntheticChick EmbryoDose-Response Relationship, DrugFlavanonesHumansInhibitory Concentration 50Molecular StructureNeuroprotective AgentsStructure-Activity RelationshipAmino AcidsAngiogenesis Inducing AgentsbaicaleinFlavanonesNeuroprotective Agentsamino acids derivativesbaicaleinchick chorioallantoic membraneneuroprotective effectSH-SY5Y cell

Identifiers

PMID31601055
PMCPMC6832219
OpenAlexW2980287330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.