Evidence map›Paper›PMID 31601054›Full record

ArticleMarine drugs2019

Actinomycin V Suppresses Human Non-Small-Cell Lung Carcinoma A549 Cells by Inducing G2/M Phase Arrest and Apoptosis via the p53-Dependent Pathway.

Shi-Qi Lin, Fu-Juan Jia, Cai-Yun Zhang, Fang-Yuan Liu, Jia-Hui Ma, Zhuo Han, Wei-Dong Xie, Xia Li

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Experimental biology and medicine (Maywood, N.J.) · 2020
    Article
  15. Article
  16. 5-HTOncoTargets and therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shi-Qi LinCollege of Marine Science, Shandong University, Weihai 264209, China. lsqsd@outlook.com.
Fu-Juan JiaCollege of Marine Science, Shandong University, Weihai 264209, China. jfj1996@outlook.com.
Cai-Yun ZhangCollege of Marine Science, Shandong University, Weihai 264209, China. caiyun617@outlook.com.
Fang-Yuan LiuCollege of Marine Science, Shandong University, Weihai 264209, China. fangyuan617@outlook.com.
Jia-Hui MaCollege of Marine Science, Shandong University, Weihai 264209, China. sdumjh@hotmail.com.
Zhuo HanCollege of Marine Science, Shandong University, Weihai 264209, China. hanzhuo1013@gmail.com.
Wei-Dong XieCollege of Marine Science, Shandong University, Weihai 264209, China. wdxie@sdu.edu.cn.ORCID 0000-0003-2781-922X
Xia LiCollege of Marine Science, Shandong University, Weihai 264209, China. xiali@sdu.edu.cn.
Shandong University · CN

Funding

Fundamental Research Funds for the Central Universities No.2019ZRJC004National Natural Science Foundation of China No. 81273532Natural Science Foundation of Shandong Province No. ZR2019MH001
6 · The paper itself

Abstract

Actinomycin V, extracted and separated from marine-derived actinomycete

Indexed as

A549 CellsApoptosisCarcinoma, Non-Small-Cell LungCell Cycle CheckpointsCell Line, TumorCyclin-Dependent Kinase Inhibitor p21DactinomycinG2 Phase Cell Cycle CheckpointsHumansLung NeoplasmsMitosisProto-Oncogene Proteins c-bcl-2Tumor Suppressor Protein p53Cyclin-Dependent Kinase Inhibitor p21DactinomycinProto-Oncogene Proteins c-bcl-2TP53 protein, humanTumor Suppressor Protein p53actinomycinapoptosiscell cycle arrestlung cancerP53

Identifiers

PMID31601054
PMCPMC6835885
OpenAlexW2979813018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.