Evidence map›Paper›PMID 31600996›Full record

ArticleMolecules (Basel, Switzerland)2019

Auriculatone Sulfate Effectively Protects Mice Against Acetaminophen-Induced Liver Injury.

Liangcai Lin, Huanyu Guan, Rui Li, Xiangming Liao, Feifei Zhao, Min Wang, Jing Li, Guobo Xu, Xun He, Jinjuan Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Potential use of garlic products in ruminant feeding: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Review
  2. Article
  3. Article
  4. Frontiers in pharmacology · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Liangcai LinState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. llcwx321@163.com.
Huanyu GuanState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. guanhuanyu630@163.com.
Rui LiState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. lirui_318@163.com.
Xiangming LiaoState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. stanley_liaoxm@163.com.
Feifei ZhaoState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. zffei0225@sina.com.
Min WangState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. Lizhudele365@sina.com.
Jing LiState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. nigel_lijing@163.com.
Guobo XuState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. xguobo@163.com.
Xun HeGuizhou Provincial Key Laboratory of Pharmaceutics, Guizhou 550004, China. hexun224@gmc.edu.cn.
Jinjuan ZhangSchool of Basic Medical Sciences, Guizhou Medical University, Guizhou 550025, China. zjj216@163.com.
Yongjun LiEngineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guizhou 550004, China. liyongjun026@126.com.ORCID 0000-0002-0479-6259
Yonglin WangEngineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guizhou 550004, China. gywyl@gmc.edu.cn.
Meng ZhouState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. qingfeng476281051@163.com.
Shanggao LiaoState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guizhou 550025, China. lshangg@163.com.
Guiyang Medical University · CN

Funding

Excellent Scientific and Technological Young Talent of Guizhou Province [2015]32Innovation and Entrepreneurship Training Program for College Students 201610660034Joint Foundation of Guizhou Province Department of Science and Technology and Guizhou Medical University [2015]7357National Natural Science Foundation of China 81260506
6 · The paper itself

Abstract

Acetaminophen (APAP) overdose is very common worldwide and has been widely recognized as the leading cause of drug-induced liver injury in the Western world. In our previous investigation, auriculatone, a natural product firstly obtained from

Indexed as

AcetaminophenAnalgesics, Non-NarcoticAnimalsChemical and Drug Induced Liver InjuryCytokinesInflammation MediatorsLiverMiceMitochondriaMolecular StructureOxidative StressProtective AgentsReactive Oxygen SpeciesAcetaminophenAnalgesics, Non-NarcoticCytokinesInflammation MediatorsProtective AgentsReactive Oxygen SpeciesAacetaminophen-induced hepatotoxicityauriculatone sulfateCYPs inhibitionhepatoprotective effectinflammationoxidative stress

Identifiers

PMID31600996
PMCPMC6832223
OpenAlexW2979898703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.