Evidence map›Paper›PMID 31600973›Full record

ArticleInternational journal of molecular sciences2019

Effect of Zinc Supplementation on Renal Anemia in 5/6-Nephrectomized Rats and a Comparison with Treatment with Recombinant Human Erythropoietin.

Hui-Lin Feng, Yen-Hua Chen, Sen-Shyong Jeng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hui-Lin FengDepartment of Food Science, College of Life Sciences, National Taiwan Ocean University, Keelung 20224, Taiwan. fhl1430@gmail.com.
Yen-Hua ChenDepartment of Basic Medicine, The Center of Translational Medicine, Xiamen Medical College, Xiamen 361023, China. yanhua09123@hotmail.com.ORCID 0000-0003-3576-1371
Sen-Shyong JengDepartment of Food Science, College of Life Sciences, National Taiwan Ocean University, Keelung 20224, Taiwan. jengss@mail.ntou.edu.tw.ORCID 0000-0001-5648-8381
National Taiwan Ocean University · TWXiamen University · CN

Funding

National Taiwan Ocean University 108J13081The Program for New Century Excellent Talents in Fujian Province University 20190093
6 · The paper itself

Abstract

Anemia is a severe complication in patients with chronic kidney disease (CKD). Treatment with exogenous erythropoietin (EPO) can correct anemia in many with CKD. We produced 5/6-nephrectomized rats that became uremic and anemic at 25 days post surgery. Injection of the anemic 5/6-nephrectomized rats with 2.8 mg zinc/kg body weight raised their red blood cell (RBC) levels from approximately 85% of the control to 95% in one day and continued for 4 days. We compared the effect of ZnSO

Indexed as

Dietary SupplementsAnemiaAnimalsBiomarkersBone Marrow CellsDisease Models, AnimalErythrocyte IndicesErythropoiesisErythropoietinHumansRatsRecombinant ProteinsRenal Insufficiency, ChronicZincZinc SulfateBiomarkersEPO protein, humanErythropoietinRecombinant ProteinsZincZinc Sulfate5/6-nephrectomized ratschronic kidney diseaseEPO productionrenal anemiazinc supplementation

Identifiers

PMID31600973
PMCPMC6829362
OpenAlexW2979479498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.