Evidence map›Paper›PMID 31600932›Full record

ArticleSensors (Basel, Switzerland)2019

A Low-Cost Micro-Volume Nephelometric System for Quantitative Immunoagglutination Assays.

Qiqi Sun, Wei Zheng, Chao Lin, Dongxuan Shen

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Nephelometry as a simple tool to monitor the disassembly of polymeric nanoparticles.Analytical methods : advancing methods and applications · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Qiqi SunResearch Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Key Laboratory for Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. qsunaa@connect.ust.hk.
Wei ZhengResearch Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Key Laboratory for Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. zhengwei@siat.ac.cn.
Chao LinEdan Instruments, Inc., Shenzhen 518067, China. linchao@edan.com.cn.
Dongxuan ShenEdan Instruments, Inc., Shenzhen 518067, China. dshen@edan.com.cn.
Edan (China) · CNChinese Academy of Sciences · CNShenzhen Institutes of Advanced Technology · CN

Funding

National Key Research and Development Program of China 2017YFC0110200Natural Science Foundation of Guangdong Province 2017A030310308the Scientific Instrument Innovation Team of Chinese Academy of Sciences GJJSTD20180002
6 · The paper itself

Abstract

Immunoassays have been widely used in scientific research and clinical diagnosis due to their versatile detection capability and high specificity. Immunoagglutination assays are kinds of immunoassay, which can simply and rapidly measure the concentration of analytes. In this work, we developed a low-cost micro-volume nephelometric system for quantitative immunoagglutination assays. We used off-the-shelf components to build the system, and the total cost of key components is only about 20 US dollars. The total detection volume in our system was as low as 3 µL, which could significantly reduce the reagent cost and required sample volume. We further evaluated the system performance via the immunoagglutination assay to measure the concentration of C-reactive protein, a plasma protein with levels rising in response to inflammation. The results demonstrated that our system could measure the concentration of analytes with relatively high sensitivity and precision within four minutes, and has high potential to be applied for clinical diagnostic tests.

Indexed as

Costs and Cost AnalysisAgglutination TestsC-Reactive ProteinHumansImaging, Three-DimensionalImmunoassayNephelometry and TurbidimetryScattering, RadiationC-Reactive ProteinC-reactive proteinimmunoagglutination assayimmunoassaylight scatteringnephelometry

Identifiers

PMID31600932
PMCPMC6832725
OpenAlexW2980177425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.