ArticlePediatric research2020
Psychosocial and medical adversity associated with neonatal neurobehavior in infants born before 30 weeks gestation.
Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Early interventions with parental participation and their implications on the neurodevelopment of premature children: a systematic review and meta-analysis.European child & adolescent psychiatry · 2025Pooled it
- Neurobehavioral Profiles in Low-Risk Infants: Associations With Prenatal Maternal Biobehavior and Birth Characteristics.Developmental psychobiology · 2025Article
- Experiences of parents with very premature-born children at risk of neurodevelopmental disorders: A qualitative study.Nursing in critical care · 2025Article
- Abnormal neurobehavior profiles observed in the newborn period following low-to-moderate prenatal alcohol exposure.Alcohol, clinical & experimental research · 2025Article
- Neurobehavioral outcomes of preterm infants: toward a holistic approach.Pediatric research · 2025Review
- Contributions of prenatal risk factors and neonatal epigenetics to cognitive outcome in children born very preterm.Developmental psychology · 2024Article
- Epigenetic associations in HPA axis genes related to bronchopulmonary dysplasia and antenatal steroids.Pediatric research · 2024Article
- Preeclampsia, Fetal Growth Restriction, and 24-Month Neurodevelopment in Very Preterm Infants.JAMA network open · 2024Article
- Risk Factors for Postpartum Depression and Severe Distress among Mothers of Very Preterm Infants at NICU Discharge.American journal of perinatology · 2024Article
- Review
- Infant massage as a stress management technique for parents of hospitalized extremely preterm infants.Infant mental health journal · 2024Article
- Spanish Translation and Cultural Adaptations of Physical Therapy Parent Educational Materials for Use in Neonatal Intensive Care.Patient preference and adherence · 2024Article
- Epigenetic age acceleration, neonatal morbidities, and neurobehavioral profiles in infants born very preterm.Epigenetics · 2023Article
- Parent Perspectives: Part 1-Considerations for Changing the NICU Culture.Children (Basel, Switzerland) · 2023Article
- Maternal Prenatal Risk Phenotypes and Neurobehavioral Outcomes among Infants Born Very Preterm.The Journal of pediatrics · 2023Article
- Parent and Therapist Perceptions of the Feasibility, Acceptability, and Benefits of a Weekly Therapist-Led Massage Program for Extremely Preterm Infants in Neonatal Intensive Care.Children (Basel, Switzerland) · 2023Article
- Prenatal and perinatal factors associated with neonatal neurobehavioral profiles in the ECHO Program.Pediatric research · 2023Article
- Environmental influences on child health outcomes: cohorts of individuals born very preterm.Pediatric research · 2023Review
- Acoustic Cry Characteristics in Preterm Infants and Developmental and Behavioral Outcomes at 2 Years of Age.JAMA network open · 2023Article
- Serial neuroimaging of brain growth and development in very preterm infants receiving tailored neuropromotive support in the NICU. Protocol for a prospective cohort study.Frontiers in pediatrics · 2023Article
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundPsychosocial adversity escalates medical risk for poor outcomes in infants born <30 weeks gestation. Neonatal neurobehavior and maternal psychological and socioenvironmental assessments may identify the earliest specific intervention needs. We hypothesized that maternal prenatal anxiety, depression, and adverse medical and socioenvironmental conditions would be associated with less optimal neonatal neurobehavior at neonatal intensive care unit (NICU) discharge.
methodsWe studied 665 infants at 9 university NICUs. Risk indices of socioenvironmental, maternal, and neonatal medical factors were obtained from standardized, structured maternal interviews and medical record reviews. Brain injuries were classified by consensus ultrasonogram readings. NICU Network Neurobehavioral Scale (NNNS) exams were conducted at NICU discharge.
resultsOn the NNNS, generalized estimating equations indicated infants of mothers with prenatal anxiety had less optimal attention, and those born to mothers with prenatal depression had increased lethargy. Maternal medical complications predicted suboptimal reflexes. Socioenvironmental risk predicted lower self-regulation and movement quality. Infants with more severe neonatal medical complications had lower attention, increased lethargy, and suboptimal reflexes.
conclusionsCombined information from the observed associations among adverse prenatal maternal medical and psychosocial conditions, and neonatal complications may assist in the early identification of infants at elevated neurobehavioral risk.
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