ArticlePloS one2019
Comparative genomic analyses reveal diverse virulence factors and antimicrobial resistance mechanisms in clinical Elizabethkingia meningoseptica strains.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Divergent roles of OmpA family proteins in physiology, stress tolerance, and virulence ofVirulence · 2026Article
- Comprehensive Phenotypic Characterization of ClinicalInternational journal of molecular sciences · 2026Article
- Molecular epidemiology and emergingAntimicrobial agents and chemotherapy · 2026Article
- From cognition to response: clinical challenges, antibiotic resistance mechanisms, and prevention and control strategies ofFrontiers in microbiology · 2026Review
- Unusual susceptibility to vancomycin inFrontiers in microbiology · 2026Review
- Article
- Comparative genomic analysis of Flavobacterium species causing columnaris disease of freshwater fish in Thailand: insights into virulence and resistance mechanisms.BMC veterinary research · 2025Article
- Molecular characterization, comparative genome analysis and resistance determinants of three clinicalFrontiers in microbiology · 2025Article
- capD deletion in the Elizabethkingia miricola capsular locus leads to capsule production deficiency and reduced virulence.Veterinary research · 2024Article
- Clinical manifestations, antimicrobial resistance and genomic feature analysis of multidrug-resistant Elizabethkingia strains.Annals of clinical microbiology and antimicrobials · 2024Article
- Clinical Characteristics and Risk Factors for Infection and Death in Critically Ill Patients with Pulmonary Infection withInfection and drug resistance · 2024Article
- Neonatal Meningitis with Septicemia byJournal of laboratory physicians · 2022Article
- Epidemiology and Characteristics ofMicroorganisms · 2022Review
- Epidemiological, clinical, and laboratory features of patients infected withFrontiers in public health · 2022Article
- Genomic analysis ofCurrent research in microbial sciences · 2022Article
- Whole genome sequencing of the multidrug-resistantFrontiers in medicine · 2022Article
- Core-Proteomics-Based Annotation of Antigenic Targets and Reverse-Vaccinology-Assisted Design of Ensemble Immunogen against the Emerging Nosocomial Infection-Causing BacteriumInternational journal of environmental research and public health · 2021Article
- Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1.Scientific reports · 2021Article
- Article
- The Impact of the Antibiotic Fosfomycin on Wastewater Communities Measured by Flow Cytometry.Frontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
Abstract
Three human clinical isolates of bacteria (designated strains Em1, Em2 and Em3) had high average nucleotide identity (ANI) to Elizabethkingia meningoseptica. Their genome sizes (3.89, 4.04 and 4.04 Mb) were comparable to those of other Elizabethkingia species and strains, and exhibited open pan-genome characteristics, with two strains being nearly identical and the third divergent. These strains were susceptible only to trimethoprim/sulfamethoxazole and ciprofloxacin amongst 16 antibiotics in minimum inhibitory tests. The resistome exhibited a high diversity of resistance genes, including 5 different lactamase- and 18 efflux protein- encoding genes. Forty-four genes encoding virulence factors were conserved among the strains. Sialic acid transporters and curli synthesis genes were well conserved in E. meningoseptica but absent in E. anophelis and E. miricola. E. meningoseptica carried several genes contributing to biofilm formation. 58 glycoside hydrolases (GH) and 25 putative polysaccharide utilization loci (PULs) were found. The strains carried numerous genes encoding two-component system proteins (56), transcription factor proteins (187~191), and DNA-binding proteins (6~7). Several prophages and CRISPR/Cas elements were uniquely present in the genomes.
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