Trial reportClinical cardiology2019
The impact of high-intensity interval training on ventricular remodeling in patients with a recent acute myocardial infarction-A randomized training intervention pilot study.
Trial report in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07118410 (Effect of Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction), which is not on this map. Cited by 30 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction
Who cites it
30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Effect of Combined Aerobic and Resistance Training on Exercise Capacity, Muscle Strength, Quality of Life, and Mortality in Patients with Coronary Heart Disease: A Systematic Review with Meta-analysis.Sports medicine - open · 2026Pooled it
- Effects of high-intensity interval training on cardiopulmonary function and quality of life in post-PCI or CABG patients with coronary heart disease: a meta-analysis.Journal of cardiothoracic surgery · 2025Pooled it
- Effects of exercise training on left ventricular systolic and diastolic function after myocardial infarction: systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Effects of high-intensity interval training on cardiopulmonary function and quality of life in patients with myocardial infarction: a meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Pooled it
- Standard Deviation of Individual Response for VOSports medicine (Auckland, N.Z.) · 2024Pooled it
- The effect of exercise on left ventricular global longitudinal strain.European journal of applied physiology · 2022Pooled it
- Effects of different exercise training programs on post-exercise [Formula: see text]OEuropean journal of applied physiology · 2026Trial
- Effect of exercise training on left ventricular remodeling in patients with myocardial infarction and possible mechanisms.World journal of clinical cases · 2021Trial
- The impact of high-intensity interval training on ventricular remodeling in patients with a recent acute myocardial infarction-A randomized training intervention pilot study.Clinical cardiology · 2019Trial
- Impact of Fitness on Cardiac Torsion and Wall Mechanics in Ischemic Heart Disease Study (FIT-TWIST).Journal of cardiovascular development and disease · 2026Article
- Effectiveness and selection of exercise prescriptions for myocardial infarction patients: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Review
- High-intensity interval training in rehabilitation of patients after myocardial infarction: a rapid review of randomized trials.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Review
- High-intensity interval training: unveiling seven key genes mediating cardioprotection in myocardial infarction.Archives of medical science : AMS · 2025Article
- Comparing the Effect of Moderate-Intensity Versus High-Intensity Interval Training Exercise on Global Longitudinal Strain (GLS) in Cardiovascular Patients: Systematic Review and Meta-Analysis.Cardiology research and practice · 2025Review
- Elevated meteorin-like protein from high-intensity interval training improves heart function via AMPK/HDAC4 pathway.Genes & diseases · 2024Article
- The Role and Potential Mechanisms of Rehabilitation Exercise Improving Cardiac Remodeling.Journal of cardiovascular translational research · 2024Review
- Interval training suppresses nod-like receptor protein 3 inflammasome activation to improve cardiac function in myocardial infarction rats by hindering the activation of the transforming growth factor-β1 pathway.Journal of cardiothoracic surgery · 2024Article
- Myocardial Work Assessment in Patients after Coronary Artery Bypass Grafting during Cardiac Rehabilitation.Journal of clinical medicine · 2023Article
- Effects of High-Intensity Interval Training on Melatonin Function and Cellular Lymphocyte Apoptosis in Sedentary Middle-Aged Men.Medicina (Kaunas, Lithuania) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundAerobic exercise training is associated with beneficial ventricular remodeling and an improvement in cardiac biomarkers in chronic stable heart failure. High-intensity interval training (HIIT) is a time-efficient method to improve
methodsNineteen post-AMI patients were randomized to either HIIT (n = 9) or usual care (n = 10). A cardiopulmonary exercise test (CPET), transthoracic echocardiography, and cardiac biomarker assessment (ie, N-terminal pro B-type natriuretic peptide levels and G protein-coupled receptor kinase 2 expression) were performed before and after a 12-week training intervention. CPET parameters including oxygen uptake efficiency slope (OUES) and
results
conclusionsIn post-AMI patients, HIIT lead to significant improvements in prognostic CPET parameters compared to usual care. HIIT was associated with favorable ventricular remodeling regarding certain echocardiographic parameters of LV function.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.