Evidence map›Paper›PMID 31599606›Full record

SynthesisJournal of consulting and clinical psychology2019

A meta-analysis of cognitive-behavioral therapy for alcohol or other drug use disorders: Treatment efficacy by contrast condition.

Molly Magill, Lara Ray, Brian Kiluk, Ariel Hoadley, Michael Bernstein, J Scott Tonigan, Kathleen Carroll

3 registry-linked trialsAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of consulting and clinical psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 134 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05579210 nacompletednot on this mapstarted 2022, after this paper: background citation

Developing and Implementing an Online Relapse Prevention Psychotherapy Program for Patients With Alcohol Use Disorder

TypeinterventionalSponsorDr. Nazanin AlaviRan2022 to 2024Enrolled60ConditionsAlcohol Use DisorderArmsOnline relapse prevention therapy, Face to face relapse prevention therapy
NCT06443294 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Development of a Smoking Cessation Video Series

TypeinterventionalSponsorWayne State UniversityRan2024 to 2024Enrolled120ConditionsTobacco Use Cessation, Tobacco SmokingArmsSmoking cessation video series.
NCT06620276 narecruitingnot on this mapstarted 2025, after this paper: background citation

Acceptance and Commitment Therapy in Patients With Alcohol Use Disorder and Comorbid Treatment-Resistant Depression Who Are Undergoing Ketamine Intervention: A Feasibility Study

TypeinterventionalSponsorCentre hospitalier de l'Université de Montréal (CHUM)Ran2025 to 2028Enrolled30ConditionsDepression - Major Depressive Disorder, Alcohol Use DisorderArmsAcceptance and Commitment Therapy, Ketamine
3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  7. Canadian guideline for the clinical management of high-risk drinking and alcohol use disorder.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Guideline
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74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Molly MagillCenter for Alcohol and Addiction Studies.
Lara RayDepartment of Psychology, University of California, Los Angeles.ORCID 0000-0002-5734-9444
Brian KilukDepartment of Psychiatry, Yale School of Medicine.
Ariel HoadleyDepartment of Behavioral and Social Sciences.ORCID 0000-0003-1360-0358
Michael BernsteinDepartment of Behavioral and Social Sciences.
J Scott ToniganDepartment of Psychology, University of New Mexico.
Kathleen CarrollDepartment of Psychiatry, Yale School of Medicine.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research and Mentoring in AA-related Mechanisms of ChangeK24AA021157 · NIAAA · UNIVERSITY OF NEW MEXICO · PI TONIGAN, J. SCOTT · 2013 to 2017
$850k
Integrating Cognitive Neuroscience Toward Understanding of Mechanisms of CBT for Alcohol Use DisordersK02AA027300 · NIAAA · YALE UNIVERSITY · PI KILUK, BRIAN D. · 2019 to 2023
$719k
A Meta-Analysis of CBT/RP Efficacy, Moderated Efficacy, and MediationR21AA026006 · NIAAA · BROWN UNIVERSITY · PI MAGILL, MOLLY · 2017 to 2018
$457k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K02 AA027300NIAAA NIH HHS K24 AA021157NIAAA NIH HHS R21 AA026006
6 · The paper itself

Abstract

objectiveThis meta-analysis examined 30 randomized controlled trials (32 study sites; 35 study arms) that tested the efficacy of cognitive-behavioral therapy (CBT) for alcohol or other drug use disorders. The study aim was to provide estimates of efficacy against three levels of experimental contrast (i.e., minimal [k = 5]; nonspecific therapy [k = 11]; specific therapy [k = 19]) for consumption frequency and quantity outcomes at early (1 to 6 months [kes = 41]) and late (8+ months [kes = 26]) follow-up time points. When pooled effect sizes were statistically heterogeneous, study-level moderators were examined.

methodThe inverse-variance weighted effect size was calculated for each study and pooled under random effects assumptions. Sensitivity analyses included tests of heterogeneity, study influence, and publication bias.

resultsCBT in contrast to minimal treatment showed a moderate and significant effect size that was consistent across outcome type and follow-up. When CBT was contrasted with a nonspecific therapy or treatment as usual, treatment effect was statistically significant for consumption frequency and quantity at early, but not late, follow-up. CBT effects in contrast to a specific therapy were consistently nonsignificant across outcomes and follow-up time points. Of 10 pooled effect sizes examined, two showed moderate heterogeneity, but multivariate analyses revealed few systematic predictors of between-study variance.

conclusionsThe current meta-analysis shows that CBT is more effective than a no treatment, minimal treatment, or nonspecific control. Consistent with findings on other evidence-based therapies, CBT did not show superior efficacy in contrast to another specific modality. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

AlcoholismCognitive Behavioral TherapyHumansOutcome Assessment, Health CareSubstance-Related Disorders

Identifiers

PMID31599606
PMCPMC6856400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.