ReviewJournal of materials science. Materials in medicine2019
Overview of natural hydrogels for regenerative medicine applications.
Review in Journal of materials science. Materials in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 325 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
325 citing papers in PubMed, 2 syntheses or guidelines pooled it, 768 citations in OpenAlex.
- Recent Advances in Hydrogels as Therapeutic Tools for Spinal Cord Injury Regeneration.Tissue engineering and regenerative medicine · 2026Pooled it
- Injectable hydrogel-based combination therapy for myocardial infarction: a systematic review and Meta-analysis of preclinical trials.BMC cardiovascular disorders · 2024Pooled it
- Hydrogel coatings for titanium implants: From smart stimuli-responsive strategies to multimodal bone regeneration.Bioactive materials · 2026Review
- Recent Advances in Nanocomposite Hydrogel Sensors for Healthcare Applications: Fabrication Techniques, Multifunctionality and Challenges.Nanomaterials (Basel, Switzerland) · 2026Review
- Nanoparticle-Hydrogel Composites for Precision Medicine.Cell biomaterials · 2026Article
- Stimulus-Responsive MOF-Hydrogel Composites for Sensing Applications.ChemPlusChem · 2026Review
- Materials advances in GTR membrane: A comprehensive review.Journal of Taibah University Medical Sciences · 2026Review
- Recent Advances in Smart Wound Healing Patches: From Passive Dressings to Intelligent Theranostic Systems.Cureus · 2026Review
- A 25-Year Review of the Use of Silanized Hydroxypropylmethylcellulose Hydrogels in Tissue Engineering and Regenerative Medicine.Macromolecular bioscience · 2026Review
- Article
- The critical role of hydrogels as an advanced polymeric scaffold in biomedicine: recent progress and challenges.RSC advances · 2026Review
- Alginate as a cytocompatible carrier for mechanically isolated stromal vascular fraction: an in vitro proof-of-concept study.Scientific reports · 2026Article
- Chitosan-cellulose hydrogels: advances in stimuli-responsive biomedical therapeutics.RSC advances · 2026Review
- Engineering complexity into protein-based biomaterials for biomedical applications.Nature reviews. Materials · 2026Article
- Tracheal Regeneration: Recent Progress in the Application of Stem Cells in Tracheal Bioengineering.International journal of molecular sciences · 2026Review
- Next-Generation Hydrogels Integrating Natural Antioxidants and Microbiome Modulators for Improved Cancer Management.Gels (Basel, Switzerland) · 2026Review
- Purification of aqueous fluids from basic fuchsine employing a new polymer of CMC-CMS hydrogel mixture: sustainability perspective.BMC chemistry · 2026Article
- Hydrogel-based drug delivery systems for enhanced tumor therapy.RSC advances · 2026Review
- Visualization Analysis and Knowledge Structure Evolution of Hydrogel Applications in Dentistry.International dental journal · 2026Article
- Marine Bioceramic Generation for Bone Tissue Regeneration: Sea Urchin (Echinometra mathaei) Exoskeleton-Derived Calcium Carbonate as a Precursor for Hydroxyapatite Synthesis, Incorporated into Chitosan Based-Hydrogel and 3D-Printed PCL Scaffold for Osteogenic Differentiation.Marine biotechnology (New York, N.Y.) · 2026Article
265 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
Hydrogels from different materials can be used in biomedical field as an innovative approach in regenerative medicine. Depending on the origin source, hydrogels can be synthetized through chemical and physical methods. Hydrogel can be characterized through several physical parameters, such as size, elastic modulus, swelling and degradation rate. Lately, research is focused on hydrogels derived from biologic materials. These hydrogels can be derived from protein polymers, such as collage, elastin, and polysaccharide polymers like glycosaminoglycans or alginate among others. Introduction of decellularized tissues into hydrogels synthesis displays several advantages compared to natural or synthetic based hydrogels. Preservation of natural molecules such as growth factors, glycans, bioactive cryptic peptides and natural proteins can promote cell growth, function, differentiation, angiogenesis, anti-angiogenesis, antimicrobial effects, and chemotactic effects. Versatility of hydrogels make possible multiple applications and combinations with several molecules on order to obtain the adequate characteristic for each scope. In this context, a lot of molecules such as cross link agents, drugs, grow factors or cells can be used. This review focuses on the recent progress of hydrogels synthesis and applications in order to classify the most recent and relevant matters in biomedical field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.