Evidence map›Paper›PMID 31599358›Full record

ReviewCurrent allergy and asthma reports2019

Comparative Review of Asthma in Farmers and Horses.

M Katie Sheats, Kaori U Davis, Jill A Poole

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Current allergy and asthma reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Environmental Management of Equine Asthma.Animals : an open access journal from MDPI · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

M Katie SheatsComparative Medicine Institute, Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, 27607, USA. mkpeed@ncsu.edu.ORCID 0000-0002-5270-4566
Kaori U DavisComparative Medicine Institute, Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, 27607, USA.
Jill A PooleDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Nebraska Medical Center, 985990 Nebraska Medical Center, Omaha, NE, 68198-5990, USA.ORCID 0000-0002-6236-2563
North Carolina State University · USUniversity of Nebraska Medical Center · US

Funding

Role of pattern recognition receptors in organic dust-induced airway inflammationR01ES019325 · NIEHS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI POOLE, JILL A · 2010 to 2020
$3.7M
NIEHS NIH HHS R01 ES019325
6 · The paper itself

Abstract

purpose of reviewFarmers are routinely exposed to organic dusts and aeroallergens that can have adverse respiratory health effects including asthma. Horses are farm-reared large animals with similar exposures and can develop equine asthma syndrome (EAS). This review aims to compare the etiology, pathophysiology, and immunology of asthma in horses compared to farmers and highlights the horse as a potential translational animal model for organic dust-induced asthma in humans. RECENT

findingsSevere EAS shares many clinical and pathological features with various phenotypes of human asthma including allergic, non-allergic, late onset, and severe asthma. EAS disease features include variable airflow obstruction, cough, airway hyperresponsiveness, airway inflammation/remodeling, neutrophilic infiltrates, excess mucus production, and chronic innate immune activation. Severe EAS is a naturally occurring and biologically relevant, translational animal disease model that could contribute to a more thorough understanding of the environmental and immunologic factors contributing to organic dust-induced asthma in humans.

Indexed as

AsthmaHorse DiseasesAnimalsEnvironmental ExposureFarmersHorsesHumansBronchitisEquine asthma syndromeInnate immunity, neutrophilic asthmaOccupational asthmaOrganic dust

Identifiers

PMID31599358
PMCPMC9116535
OpenAlexW2980011220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.