ArticleEuropean heart journal. Cardiovascular Imaging2020
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block.
Article in European heart journal. Cardiovascular Imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Ventricular preexcitation-induced subclinical LV dysfunction: Insights from pressure-strain loop imaging.American heart journal plus : cardiology research and practice · 2026Article
- Towards Phenotyping Characteristics and Mechanism of Conduction Delay in Patients With Nonischemic Heart Failure With Reduced Ejection Fraction: Insights From Cardiac Magnetic Resonance Imaging.Journal of the American Heart Association · 2025Article
- Successful cardiac resynchronization therapy reduces negative septal work in patient-specific models of dyssynchronous heart failure.PLoS computational biology · 2024Article
- 3D regional evaluation of right ventricular myocardial work from cineCT.medRxiv : the preprint server for health sciences · 2024Article
- Successful Cardiac Resynchronization Therapy Reduces Negative Septal Work in Patient-Specific Models of Dyssynchronous Heart Failure.bioRxiv : the preprint server for biology · 2024Article
- Cardiac Magnetic Resonance Identifies Responders to Cardiac Resynchronization Therapy with an Assessment of Septal Scar and Left Ventricular Dyssynchrony.Journal of clinical medicine · 2023Article
- Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop.BMC cardiovascular disorders · 2023Article
- Machine learning for spatial stratification of progressive cardiovascular dysfunction in a murine model of type 2 diabetes mellitus.PloS one · 2023Article
- Cardiac magnetic resonance imaging in patients with left bundle branch block: Patterns of dyssynchrony and implications for late gadolinium enhancement imaging.Frontiers in cardiovascular medicine · 2022Article
- Global and Regional Myocardial Work in Female Adolescents with Weight Disorders.Journal of clinical medicine · 2021Article
- Acute recoordination rather than functional hemodynamic improvement determines reverse remodelling by cardiac resynchronisation therapy.The international journal of cardiovascular imaging · 2021Article
- Presence of contractile impairment appears crucial for structural remodeling in idiopathic left bundle-branch block.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Value of quantitative analysis of left ventricular systolic function in patients on maintenance hemodialysis based on myocardial work technique.BMC cardiovascular disorders · 2021Article
- Efficiency is key.European heart journal. Cardiovascular Imaging · 2020Article
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimsRegional myocardial work may be assessed by pressure-strain analysis using a non-invasive estimate of left ventricular pressure (LVP). Strain by speckle tracking echocardiography (STE) is not always accessible due to poor image quality. This study investigated the estimation of regional myocardial work from strain by feature tracking (FT) cardiac magnetic resonance (CMR) and non-invasive LVP. METHODS AND
resultsThirty-seven heart failure patients with reduced ejection fraction, left bundle branch block (LBBB), and no myocardial scar were compared to nine controls without LBBB. Circumferential strain was measured by FT-CMR in a mid-ventricular short-axis cine view, and longitudinal strain by STE. Segmental work was calculated by pressure-strain analysis. Twenty-five patients underwent 18F-fluorodeoxyglucose (FDG) positron emission tomography. Segmental values were reported as percentages of the segment with maximum myocardial FDG uptake. In LBBB patients, net CMR-derived work was 51 ± 537 (mean ± standard deviation) in septum vs. 1978 ± 1084 mmHg·% in the left ventricular (LV) lateral wall (P < 0.001). In controls, however, there was homogeneous work distribution with similar values in septum and the LV lateral wall (non-significant). Reproducibility was good. Segmental CMR-derived work correlated with segmental STE-derived work and with segmental FDG uptake (average r = 0.71 and 0.80, respectively).
conclusionFT-CMR in combination with non-invasive LVP demonstrated markedly reduced work in septum compared to the LV lateral wall in patients with LBBB. Work distribution correlated with STE-derived work and energy demand as reflected in FDG uptake. These results suggest that FT-CMR in combination with non-invasive LVP is a relevant clinical tool to measure regional myocardial work.
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