Evidence map›Paper›PMID 31598929›Full record

ArticleEnvironmental science and pollution research international2019

Control of a toxic cyanobacterial bloom species, Microcystis aeruginosa, using the peptide HPA3NT3-A2.

Sang-Il Han, Sok Kim, Ki Young Choi, Changsu Lee, Yoonkyung Park, Yoon-E Choi

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sang-Il HanDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Korea.
Sok KimDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Korea.
Ki Young ChoiSchool of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, 16419, Korea.
Changsu LeeMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju, 61755, Korea.
Yoonkyung ParkResearch Center for Proteinaceous Materials (RCPM), Chosun University, Gwangju, 61452, Korea. y_k_park@chosun.ac.kr.
Yoon-E ChoiDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Korea. yechoi@korea.ac.kr.
Korea University · KRChosun University · KRSungkyunkwan University · KRWorld Institute of Kimchi · KR

Funding

Korea Basic Science Institute Project No. C38703Ministry of Oceans and Fisheries No. 20170488National Research Foundation of Korea NRF-2016R1D1A1B03932773
6 · The paper itself

Abstract

Microcystis aeruginosa, a species of freshwater cyanobacteria, is known to be one of the dominant species causing cyanobacterial harmful algal blooms (CyanoHABs). M. aeruginosa blooms have the potential to produce neurotoxins and peptide hepatotoxins, such as microcystins and lipopolysaccharides (LPSs). Currently, technologies for CyanoHAB control do not provide any ultimate solution because of the secondary pollution associated with the control measures. In this study, we attempted to use the peptide HPA3NT3-A2, which has been reported to be nontoxic and has antimicrobial properties, for the development of an eco-friendly control against CyanoHABs. HPA3NT3-A2 displayed significant algicidal effects against M. aeruginosa cells. HPA3NT3-A2 induced cell aggregation and flotation (thereby facilitating harvest), inhibited cell growth through sedimentation, and eventually destroyed the cells. HPA3NT3-A2 had no algicidal effect on other microalgal species such as Haematococcus pluvialis and Chlorella vulgaris. Additionally, HPA3NT3-A2 was not toxic to Daphnia magna. The algicidal mechanism of HPA3NT3-A2 was intracellular penetration. The results of this study suggest the novel possibility of controlling CyanoHABs using HPA3NT3-A2.

Indexed as

AnimalsAnti-Bacterial AgentsChlorella vulgarisCyanobacteriaDaphniaFresh WaterHarmful Algal BloomMicroalgaeMicrocystinsMicrocystisAnti-Bacterial AgentsmicrocystinMicrocystinsAlgicidal peptideAlgicideCyanobacterial bloomsEco-friendly mitigationHABsHPA3NT3-A2Microcystis aeruginosa

Identifiers

PMID31598929
OpenAlexW2979366030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.