ReviewJournal of neural transmission (Vienna, Austria : 1996)2020
Cortical pain processing in migraine.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Human assumed central sensitization in interictal migraine: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine.Brain topography · 2026Article
- Volume of the hypothalamus and its subunits in patients with episodic migraine without aura during interictal periods.The journal of headache and pain · 2025Article
- The moderating role of cognitive fusion in the relationship between trait and state anger in episodic migraine, chronic migraine and healthy controls.Scientific reports · 2025Article
- Local Dynamic Stability of Trunk During Gait Can Detect Dynamic Imbalance in Subjects with Episodic Migraine.Sensors (Basel, Switzerland) · 2024Article
- Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024Review
- Endogenous pain modulation after sleep restriction in migraine: a blinded crossover study.The journal of headache and pain · 2024Article
- Brain connectome-based imaging markers for identifiable signature of migraine with and without aura.Quantitative imaging in medicine and surgery · 2024Article
- Relationship between Contingent Negative Variation and afterimage duration in migraine patients.Frontiers in neurology · 2024Article
- Migraine: from pathophysiology to treatment.Journal of neurology · 2023Review
- Migraine with aura: less control over pain and fragrances?The journal of headache and pain · 2023Article
- Observational
- Migraine Type-Dependent Patterns of Brain Activation After Facial and Intranasal Trigeminal Stimulation.Brain topography · 2023Article
- Whole brain surface-based morphometry and tract-based spatial statistics in migraine with aura patients: difference between pure visual and complex auras.Frontiers in human neuroscience · 2023Article
- A Hypothalamic Mechanism Regulates the Duration of a Migraine Attack: Insights from Microstructural and Temporal Complexity of Cortical Functional Networks Analysis.International journal of molecular sciences · 2022Article
- Pain thresholds and suprathreshold pain after sleep restriction in migraine - A blinded crossover study.Cephalalgia : an international journal of headache · 2022Article
- Neuromodulation for Chronic Daily Headache.Current pain and headache reports · 2022Review
- Altered effective connectivity in migraine patients during emotional stimuli: a multi-frequency magnetoencephalography study.The journal of headache and pain · 2022Article
- Alteration in Functional Magnetic Resonance Imaging Signal Complexity Across Multiple Time Scales in Patients With Migraine Without Aura.Frontiers in neuroscience · 2022Article
- Hypothalamic structural integrity and temporal complexity of cortical information processing at rest in migraine without aura patients between attacks.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among painful disorders, migraine is distinguishable by its chronic pathology and episodic clinical manifestation. Only a small percentage of patients with migraine progress to a chronic form of migraine. Both peripheral and central portions of the trigeminal system are involved in the pathophysiology of migraine pain, as they are involved in the processes of peripheral and central sensitization, alongside various subcortical and cortical brain structures. This review focuses on clinical, neurophysiological, and neuroimaging data underscoring cortical pain processing in migraine. Data obtained from quantitative sensory testings are inconclusive and support the involvement of the peripheral portion of the trigeminovascular system as indirect evidence of peripheral sensitization, solely during the headache phase. The assessment of subjective pain intensity in response to several painful modalities has not been conclusive for the clear state of central sensitization in between migraine attacks but for the subclinical allodynia state that defines the boundary between behavioural responses and an irritable nervous state. Modulation of the brainstem and midbrain pain pathways, in conjunction with the thalamic and thalamocortical pathways, may be critical for the initiation and maintenance of migraine attacks. Several studies using different neuroimaging techniques have demonstrated that brains experiencing migraine undergo plastic changes in both microstructure and macrostructure and in the functioning of cortical networks, which may manifest early in the life of a patient with migraine. Further studies are required to understand how specific these results are to migraine relative to other painful disorders.
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Registered trials
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