ArticleSchizophrenia bulletin2020
Are Negative Symptoms Merely the "Real World" Consequences of Deficits in Social Cognition?
Article in Schizophrenia bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Emotion Processing and Its Relationship to Social Functioning and Symptoms in Psychotic Disorder: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2025Pooled it
- Disentangling the Relationships Between the Clinical Symptoms of Schizophrenia Spectrum Disorders and Theory of Mind: A Meta-analysis.Schizophrenia bulletin · 2023Pooled it
- Social functioning and brain imaging in individuals at clinical high-risk for psychosis: A systematic review.Schizophrenia research · 2021Pooled it
- Relationships between empathy, symptoms, and functioning in first episode psychosis.Schizophrenia research · 2026Trial
- Social and Clinical Factors Associated With Antipsychotic Medication Discontinuation in Patients With Schizophrenia.International journal of methods in psychiatric research · 2026Article
- Theory of mind difficulties in people with social anhedonia: Evidence from behavioural and task-based functional magnetic resonance imaging findings.Schizophrenia research. Cognition · 2026Article
- Article
- Relationship between cognitive reserve (education), social cognition and negative symptoms.Schizophrenia research. Cognition · 2025Article
- Jumping to Conclusions and Facial Emotion Recognition in First-Episode Psychosis: Longitudinal Insights from the Gap Follow-Up Study.Clinical neuropsychiatry · 2025Article
- Adaptation of the virtual assessment of mentalizing ability and evaluation of its utility and psychometric properties in Chinese individuals on the schizophrenia spectrum.Schizophrenia (Heidelberg, Germany) · 2025Article
- How do negative symptoms and social cognitive impairments overlap? Clustering analyses on patients living with schizophrenia-spectrum disorder.Social cognitive and affective neuroscience · 2025Article
- Article
- Motivation and Pleasure Deficits Undermine the Benefits of Social Affiliation in Psychosis.Clinical psychological science : a journal of the Association for Psychological Science · 2024Article
- Article
- Intermittent Theta Burst Stimulation Combined with Cognitive Training to Improve Negative Symptoms and Cognitive Impairment in Schizophrenia: A Pilot Study.Brain sciences · 2024Article
- Diminished Auditory Cortex Dynamic Range and its Clinical Correlates in First Episode Psychosis.Schizophrenia bulletin · 2023Article
- Mediation Effects of Social Cognition on the Relationship between Neurocognition and Social Functioning in Major Depressive Disorder and Schizophrenia Spectrum Disorders.Journal of personalized medicine · 2023Article
- Emotion regulation and social knowledge in youth at clinical high-risk for psychosis and outpatients with chronic schizophrenia: Associations with functional outcome and negative symptoms.Early intervention in psychiatry · 2023Article
- Cognitive Dysfunction as a Risk Factor for Psychosis.Current topics in behavioral neurosciences · 2023Article
- Association of Transferrin Gene Polymorphism with Cognitive Deficits and Psychiatric Symptoms in Patients with Chronic Schizophrenia.Journal of clinical medicine · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
Abstract
Many investigations have demonstrated that negative symptoms and social cognitive deficits in schizophrenia play a large role in determining functional outcomes and ultimately long-term prognosis. Given this, there is increasing interest in understanding the relationship between these two symptom domains, particularly since studies have consistently found moderate to large associations between them. This shared variance raises a key question: to what degree do these two categories of symptoms arise from overlapping or identical changes in brain function? In other words, do some or all negative symptoms represent merely the downstream effects of social cognition deficits on daily functioning? In this commentary, the evidence for and against this possibility, limitations of currently validated empirical measurements of these symptoms, and directions for further investigation of this hypothesis are discussed. Understanding the shared and distinct mechanisms of these disabling deficits will have important implications for the design of novel, personalized treatments for psychotic illness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.