ArticleTherapeutic advances in endocrinology and metabolism2019
Hospital outcomes and cumulative burden from complications in type 2 diabetic sepsis patients: a cohort study using administrative and hospital-based databases.
Article in Therapeutic advances in endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Association Between Type 2 Diabetes Mellitus and Sepsis Outcomes: A Systematic Review and Meta-Analysis.Cureus · 2026Review
- The interplay between type 2 diabetes mellitus and sepsis: a scoping review.International journal of medical sciences · 2026Article
- Sleep Disorders and Stroke: Pathophysiological Links, Clinical Implications, and Management Strategies.Medical sciences (Basel, Switzerland) · 2025Review
- Predictive models and determinants of mortality among T2DM patients in a tertiary hospital in Ghana, how do machine learning techniques perform?BMC endocrine disorders · 2025Article
- Observational
- COVID-19 Outcomes and Diabetes Mellitus: A Comprehensive Multicenter Prospective Cohort Study.Microorganisms · 2023Article
- Effects of colchicine use on ischemic and hemorrhagic stroke risk in diabetic patients with and without gout.Scientific reports · 2022Article
- Risk for hypoglycemic emergency with levofloxacin use, a population-based propensity score matched nested case-control study.PloS one · 2022Article
- Correlation Analysis of Blood Glucose Level with Inflammatory Response and Immune Indicators in Patients with Sepsis.Disease markers · 2022Article
- Colchicine Is a Weapon for Managing the Heart Disease Among Interstitial Lung Disease With Viral Infection: Have We Found the Holy Grail?Frontiers in cardiovascular medicine · 2022Article
- Divergent Sepsis Pathophysiology in Older Adults.Antioxidants & redox signaling · 2021Review
- Type 2 Diabetic Sepsis Patients Have a Lower Mortality Rate in Pioglitazone Use: A Nationwide 15-Year Propensity Score Matching Observational Study in Taiwan.Emergency medicine international · 2021Article
- Stress Hyperglycemia and Mortality in Subjects With Diabetes and Sepsis.Critical care explorations · 2020Article
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7 authors.
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Abstract
backgroundThe association between type 2 diabetes and hospital outcomes of sepsis remains controversial when severity of diabetes is not taken into consideration. We examined this association using nationwide and hospital-based databases.
methodsThe first part of this study was mainly conducted using a nationwide database, which included 1.6 million type 2 diabetic patients. The diabetic complication burden was evaluated using the adapted Diabetes Complications Severity Index score (aDCSI score). In the second part, we used laboratory data from a distinct hospital-based database to make comparisons using regression analyses.
resultsThe nationwide study included 19,719 type 2 diabetic sepsis patients and an equal number of nondiabetic sepsis patients. The diabetic sepsis patients had an increased odds ratio (OR) of 1.14 (95% confidence interval 1.1-1.19) for hospital mortality. The OR for mortality increased as the complication burden increased [aDCSI scores of 0, 1, 2, 3, 4, and ⩾5 with ORs of 0.91, 0.87, 1.14, 1.25, 1.56, and 1.77 for mortality, respectively (all
conclusionsFor type 2 diabetic sepsis patients, the diabetes-related complication burden was the major determinant of hospital mortality rather than diabetes
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