Evidence map›Paper›PMID 31598135›Full record

ArticleTherapeutic advances in gastroenterology2019

Effects of probiotics on nonalcoholic fatty liver disease: a systematic review and meta-analysis.

Yao Tang, Juan Huang, Wen Yue Zhang, Si Qin, Yi Xuan Yang, Hong Ren, Qin-Bing Yang, Huaidong Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 12 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 12 syntheses or guidelines pooled it, 87 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yao TangDepartment of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Juan HuangDepartment of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wen Yue ZhangDepartment of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Si QinCenter for Endocrine Diseases, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yi Xuan YangInstitute for Viral Hepatitis, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hong RenInstitute for Viral Hepatitis, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qin-Bing YangDepartment of Clinical Nutrition, Tsinghua University, Beijing, China.
Huaidong HuDepartment of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, No.76, Linjiang Road, Chongqing 400010, China.ORCID https://orcid.org/0000-0003-2332-2304
Dalian Medical University · CNChongqing Medical University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonalcoholic fatty liver disease (NAFLD) has become prevalent in recent decades, especially in developed countries, and approaches for the prevention and treatment of NAFLD are not clear. The aim of this research was to analyze and summarize randomized controlled trials that investigated the effects of probiotics on NAFLD.

methodsSeven databases (PubMed, Embase, the Web of Science, the Cochrane Library, China National Knowledge Infrastructure, Wan Fang Data, and VIP Database) were searched. Then, eligible studies were identified. Finally, proper data extraction, synthesis and analysis were performed by trained researchers.

resultsAnthropometric parameters: with use of probiotics weight was reduced by 2.31 kg, and body mass index (BMI) was reduced by 1.08 kg/m

conclusionProbiotic treatment or supplementation is a promising therapeutic method for NAFLD.

Indexed as

Anthropometric parametersCytokinesDegree of liver fat infiltrationLipid profilesLiver functionMeta-analysisNAFLDPlasma glucoseProbiotics

Identifiers

PMID31598135
PMCPMC6764034
OpenAlexW2975167027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.